Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000585399> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2000585399 endingPage "38" @default.
- W2000585399 startingPage "35" @default.
- W2000585399 abstract "A series of 9 infants, ranging in age from 3 months to 5 years (average: 2 years), suffered from idiopathic myopathic carnitine deficiency presenting as hypotonia and motor delay. Secondary carnitine deficiency was eliminated by appropriate tests. Muscle carnitine concentration ranged from 2.3-7.1 nmol/mg non-collagen protein (NCP; average: 4.87 nmol/mg NCP; normal: 22 +/- 6 nmol/mg NCP). Lipid accumulation in muscle was observed in 2 of 8 patients. Therapy with L-carnitine (100 mg/kg/day in most patients) was given with clinical and laboratory follow-up 6 months later. In 7 of 9 patients, muscle tone and motor function improved. Muscle carnitine concentration increased to a range of 2.7-23.4 nmol/mg (average: 12.27 nmol/mg). In some patients the muscle carnitine content multiplied by a factor of 3-4, but carnitine concentration reached the normal range in only 2 patients. Most infants with idiopathic carnitine deficiency did benefit from 6 months of therapy; however, in order to achieve full recovery the duration of therapy should probably continue for longer periods, with a dose of not less than 100 mg/kg/day." @default.
- W2000585399 created "2016-06-24" @default.
- W2000585399 creator A5006514294 @default.
- W2000585399 creator A5011485159 @default.
- W2000585399 creator A5045427973 @default.
- W2000585399 creator A5060588546 @default.
- W2000585399 creator A5091012284 @default.
- W2000585399 date "1993-01-01" @default.
- W2000585399 modified "2023-09-26" @default.
- W2000585399 title "Infantile idiopathic myopathic carnitine deficiency: Treatment with l-carnitine" @default.
- W2000585399 cites W1971437635 @default.
- W2000585399 cites W1989341494 @default.
- W2000585399 cites W2010579792 @default.
- W2000585399 cites W2017731348 @default.
- W2000585399 cites W2023484190 @default.
- W2000585399 cites W2036520233 @default.
- W2000585399 cites W2053167233 @default.
- W2000585399 cites W2063367773 @default.
- W2000585399 cites W2069826246 @default.
- W2000585399 cites W2094572802 @default.
- W2000585399 cites W2122211433 @default.
- W2000585399 cites W2170170270 @default.
- W2000585399 cites W2307853259 @default.
- W2000585399 doi "https://doi.org/10.1016/0887-8994(93)90007-y" @default.
- W2000585399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8452598" @default.
- W2000585399 hasPublicationYear "1993" @default.
- W2000585399 type Work @default.
- W2000585399 sameAs 2000585399 @default.
- W2000585399 citedByCount "26" @default.
- W2000585399 countsByYear W20005853992012 @default.
- W2000585399 countsByYear W20005853992013 @default.
- W2000585399 countsByYear W20005853992015 @default.
- W2000585399 countsByYear W20005853992016 @default.
- W2000585399 countsByYear W20005853992017 @default.
- W2000585399 countsByYear W20005853992018 @default.
- W2000585399 countsByYear W20005853992020 @default.
- W2000585399 countsByYear W20005853992021 @default.
- W2000585399 countsByYear W20005853992022 @default.
- W2000585399 crossrefType "journal-article" @default.
- W2000585399 hasAuthorship W2000585399A5006514294 @default.
- W2000585399 hasAuthorship W2000585399A5011485159 @default.
- W2000585399 hasAuthorship W2000585399A5045427973 @default.
- W2000585399 hasAuthorship W2000585399A5060588546 @default.
- W2000585399 hasAuthorship W2000585399A5091012284 @default.
- W2000585399 hasConcept C126322002 @default.
- W2000585399 hasConcept C134018914 @default.
- W2000585399 hasConcept C2777300911 @default.
- W2000585399 hasConcept C2778435403 @default.
- W2000585399 hasConcept C2779546488 @default.
- W2000585399 hasConcept C2911046722 @default.
- W2000585399 hasConcept C71924100 @default.
- W2000585399 hasConceptScore W2000585399C126322002 @default.
- W2000585399 hasConceptScore W2000585399C134018914 @default.
- W2000585399 hasConceptScore W2000585399C2777300911 @default.
- W2000585399 hasConceptScore W2000585399C2778435403 @default.
- W2000585399 hasConceptScore W2000585399C2779546488 @default.
- W2000585399 hasConceptScore W2000585399C2911046722 @default.
- W2000585399 hasConceptScore W2000585399C71924100 @default.
- W2000585399 hasIssue "1" @default.
- W2000585399 hasLocation W20005853991 @default.
- W2000585399 hasLocation W20005853992 @default.
- W2000585399 hasOpenAccess W2000585399 @default.
- W2000585399 hasPrimaryLocation W20005853991 @default.
- W2000585399 hasRelatedWork W1975536848 @default.
- W2000585399 hasRelatedWork W1990720116 @default.
- W2000585399 hasRelatedWork W1996144609 @default.
- W2000585399 hasRelatedWork W2024620706 @default.
- W2000585399 hasRelatedWork W2050462086 @default.
- W2000585399 hasRelatedWork W2070787133 @default.
- W2000585399 hasRelatedWork W2092190508 @default.
- W2000585399 hasRelatedWork W2126771929 @default.
- W2000585399 hasRelatedWork W2148113506 @default.
- W2000585399 hasRelatedWork W68689877 @default.
- W2000585399 hasVolume "9" @default.
- W2000585399 isParatext "false" @default.
- W2000585399 isRetracted "false" @default.
- W2000585399 magId "2000585399" @default.
- W2000585399 workType "article" @default.