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- W2000586119 abstract "In addition to single-nucleotide variations and small insertions-deletions (indels), largersized structural variations (for example, insertions, deletions, inversions, segmental duplications and copy-number polymorphisms) contribute to human genetic diversity. In almost all recent structural variation discovery (SVD) studies, short reads from a donor genome have been mapped to a reference genome as a first step. The accuracy of such an SVD study is directly correlated to the accuracy of this mapping step, which also provides the main computational bottleneck of the SVD study." @default.
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- W2000586119 date "2010-08-01" @default.
- W2000586119 modified "2023-10-01" @default.
- W2000586119 title "mrsFAST: a cache-oblivious algorithm for short-read mapping" @default.
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- W2000586119 doi "https://doi.org/10.1038/nmeth0810-576" @default.
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