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- W2000586749 abstract "THE PHYSIOLOGICAL responses to certain hormones are complicated by the development of resistant substances, the so-called antihormones. At present the most clearly defined of these is the antithyroid substance described by Blum (1). Although Collip and Selye et al. (2) have succeeded in developing inhibitory substances in the blood of animals injected with large amounts of gonadotropic extracts over long periods of time, such antihormones have never been shown to occur normally in human blood serum. The present problem is concerned with the activating effect of the gonadotropic substances on the growth of the immature rat ovary. The specific question investigated was whether or not an antigonadotropic hormone normally exists in human blood serum. Human pituitary glands were obtained at autopsy and dehydrated overnight in 98? acetone. The anterior lobes were separated out and ground to a fine powder. Fifty glands were pooled, uniformly mixed and stored in the ice box at 4° C. to be used as the stock materi..." @default.
- W2000586749 created "2016-06-24" @default.
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- W2000586749 date "1940-03-01" @default.
- W2000586749 modified "2023-09-28" @default.
- W2000586749 title "THE ANTIGONADOTROPIC HORMONES IN NORMAL HUMAN BLOOD SERUM1" @default.
- W2000586749 doi "https://doi.org/10.1210/endo-26-3-369" @default.
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