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- W2000586976 abstract "This communication reports that cystine can be converted rapidly and quantitatively to cysteic acid by iodate in 0.1–1M HCl. It also reports on the reaction with insulin in 0.5M HCl; the amount of iodate consumed is nearly that required to oxidize two disulfide groups, and an insoluble product is formed, which can be separated by electrophoresis into two components. The molecular of insulin consists of two polypeptide chains, A and B, linked by two disulfide bonds, and the A-chain contains a third disulfide bond. It appears that the principal action of iodate is to cleave the interchain disulfide bonds." @default.
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- W2000586976 date "1966-10-01" @default.
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- W2000586976 title "The reaction of iodate with cystine and with insulin" @default.
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- W2000586976 doi "https://doi.org/10.1016/0006-291x(66)90585-7" @default.
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