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• W2000588494 abstract "Conventional functional imaging paradigms use periods of repetitive task performance to generate sustained functional signal changes. We have developed a technique of imaging the small, transient signal changes that occur after single cognitive events. The technique uses echo-planar imaging at 3 T to generate functional images of the whole brain with a temporal resolution of 3 seconds. It uses a signal averaging technique to create time sweeps of functional activity. After a single cognitive event, widely distributed patterns of brain activation can be detected and their time course measured. This technique enables the individual cognitive tasks that constitute a paradigm to be analyzed separately and compared. We describe the application of this new technique to separate the cognitive elements in a simple go/no-go motor paradigm. Comparison of activation patterns during go and no-go responses reveals hierarchical subdivision of the medial premotor cortex into an anterior region (presupplementary motor area) involved in movement decision making and a posterior region (supplementary motor area proper) directly involved in motor execution." @default.
• W2000588494 created "2016-06-24" @default.
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• W2000588494 date "1997-10-01" @default.
• W2000588494 modified "2023-10-01" @default.
• W2000588494 title "Functional magnetic resonance imaging of single motor events reveals human presupplementary motor area" @default.
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• W2000588494 doi "https://doi.org/10.1002/ana.410420414" @default.
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