FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000588613> ?p ?o ?g. }

• W2000588613 endingPage "231" @default.
• W2000588613 startingPage "227" @default.
• W2000588613 abstract "Background The role of vancomycin in surgical antimicrobial prophylaxis and high-risk patients who are most likely to benefit remains unclear. Questions/purposes We determined the impact of targeted use of vancomycin on (1) the incidence of periprosthetic joint infection (PJI); and (2) the incidence of PJI from methicillin-resistant organisms in patients undergoing revision total knee arthroplasty (TKA) at our institution. Methods In an effort to reduce PJI rates, we added vancomycin to cefazolin as surgical antimicrobial prophylaxis for patients undergoing revision TKA in October 2010. Internal data indicated a high rate of PJI in revision TKA and in particular PJI resulting from methicillin-resistant organisms, including methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE). We retrospectively reviewed infection control surveillance data on 414 revision TKAs performed between July 2008 and June 2012 (fiscal years 2009-2012). Results The overall rate of PJI in fiscal years 2009-2010 among 190 patients undergoing revision TKA was 7.89%. After the change in surgical antimicrobial prophylaxis, there was a significant reduction in PJI among patients undergoing revision TKA in fiscal years 2011-2012 to 3.13% (p = 0.046). In particular, we observed a reduction in PJI resulting from methicillin-resistant organisms over this same time period, from 4.21% to 0.89% (p = 0.049). Conclusions Targeted use of vancomycin in patients undergoing revision TKA was effective in reducing the rate of PJI and PJI resulting from methicillin-resistant organisms in an institution with a high baseline rate of PJI due to MRSA and MRSE. Identification of high-risk subgroups of patients within a surgical population can help target infection prevention strategies to those who are most likely to benefit and thus minimize potential risks (eg, selection of resistant organisms, adverse drug events) associated with broader application of such an intervention. Level of Evidence Level III, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence." @default.
• W2000588613 created "2016-06-24" @default.
• W2000588613 creator A5055790209 @default.
• W2000588613 creator A5074635554 @default.
• W2000588613 creator A5085308346 @default.
• W2000588613 creator A5088077185 @default.
• W2000588613 creator A5088286471 @default.
• W2000588613 creator A5091592847 @default.
• W2000588613 date "2014-01-01" @default.
• W2000588613 modified "2023-10-18" @default.
• W2000588613 title "Targeted Use of Vancomycin as Perioperative Prophylaxis Reduces Periprosthetic Joint Infection in Revision TKA" @default.
• W2000588613 cites W2056090497 @default.
• W2000588613 cites W74132702 @default.
• W2000588613 doi "https://doi.org/10.1007/s11999-013-3029-0" @default.
• W2000588613 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3889430" @default.
• W2000588613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23645338" @default.
• W2000588613 hasPublicationYear "2014" @default.
• W2000588613 type Work @default.
• W2000588613 sameAs 2000588613 @default.
• W2000588613 citedByCount "45" @default.
• W2000588613 countsByYear W20005886132013 @default.
• W2000588613 countsByYear W20005886132014 @default.
• W2000588613 countsByYear W20005886132015 @default.
• W2000588613 countsByYear W20005886132016 @default.
• W2000588613 countsByYear W20005886132017 @default.
• W2000588613 countsByYear W20005886132018 @default.
• W2000588613 countsByYear W20005886132019 @default.
• W2000588613 countsByYear W20005886132020 @default.
• W2000588613 countsByYear W20005886132021 @default.
• W2000588613 countsByYear W20005886132022 @default.
• W2000588613 countsByYear W20005886132023 @default.
• W2000588613 crossrefType "journal-article" @default.
• W2000588613 hasAuthorship W2000588613A5055790209 @default.
• W2000588613 hasAuthorship W2000588613A5074635554 @default.
• W2000588613 hasAuthorship W2000588613A5085308346 @default.
• W2000588613 hasAuthorship W2000588613A5088077185 @default.
• W2000588613 hasAuthorship W2000588613A5088286471 @default.
• W2000588613 hasAuthorship W2000588613A5091592847 @default.
• W2000588613 hasBestOaLocation W20005886132 @default.
• W2000588613 hasConcept C120665830 @default.
• W2000588613 hasConcept C121332964 @default.
• W2000588613 hasConcept C126322002 @default.
• W2000588613 hasConcept C141071460 @default.
• W2000588613 hasConcept C2777052132 @default.
• W2000588613 hasConcept C2778120723 @default.
• W2000588613 hasConcept C2778336525 @default.
• W2000588613 hasConcept C2778353156 @default.
• W2000588613 hasConcept C2778980435 @default.
• W2000588613 hasConcept C2779489039 @default.
• W2000588613 hasConcept C3018947069 @default.
• W2000588613 hasConcept C31174226 @default.
• W2000588613 hasConcept C4937899 @default.
• W2000588613 hasConcept C501593827 @default.
• W2000588613 hasConcept C523546767 @default.
• W2000588613 hasConcept C54355233 @default.
• W2000588613 hasConcept C61511704 @default.
• W2000588613 hasConcept C71924100 @default.
• W2000588613 hasConcept C86803240 @default.
• W2000588613 hasConcept C89423630 @default.
• W2000588613 hasConceptScore W2000588613C120665830 @default.
• W2000588613 hasConceptScore W2000588613C121332964 @default.
• W2000588613 hasConceptScore W2000588613C126322002 @default.
• W2000588613 hasConceptScore W2000588613C141071460 @default.
• W2000588613 hasConceptScore W2000588613C2777052132 @default.
• W2000588613 hasConceptScore W2000588613C2778120723 @default.
• W2000588613 hasConceptScore W2000588613C2778336525 @default.
• W2000588613 hasConceptScore W2000588613C2778353156 @default.
• W2000588613 hasConceptScore W2000588613C2778980435 @default.
• W2000588613 hasConceptScore W2000588613C2779489039 @default.
• W2000588613 hasConceptScore W2000588613C3018947069 @default.
• W2000588613 hasConceptScore W2000588613C31174226 @default.
• W2000588613 hasConceptScore W2000588613C4937899 @default.
• W2000588613 hasConceptScore W2000588613C501593827 @default.
• W2000588613 hasConceptScore W2000588613C523546767 @default.
• W2000588613 hasConceptScore W2000588613C54355233 @default.
• W2000588613 hasConceptScore W2000588613C61511704 @default.
• W2000588613 hasConceptScore W2000588613C71924100 @default.
• W2000588613 hasConceptScore W2000588613C86803240 @default.
• W2000588613 hasConceptScore W2000588613C89423630 @default.
• W2000588613 hasIssue "1" @default.
• W2000588613 hasLocation W20005886131 @default.
• W2000588613 hasLocation W20005886132 @default.
• W2000588613 hasLocation W20005886133 @default.
• W2000588613 hasLocation W20005886134 @default.
• W2000588613 hasLocation W20005886135 @default.
• W2000588613 hasOpenAccess W2000588613 @default.
• W2000588613 hasPrimaryLocation W20005886131 @default.
• W2000588613 hasRelatedWork W2028346105 @default.
• W2000588613 hasRelatedWork W2151276815 @default.
• W2000588613 hasRelatedWork W2151354686 @default.
• W2000588613 hasRelatedWork W2605536786 @default.
• W2000588613 hasRelatedWork W2610817490 @default.
• W2000588613 hasRelatedWork W2801031909 @default.
• W2000588613 hasRelatedWork W2810210275 @default.
• W2000588613 hasRelatedWork W2942429733 @default.
• W2000588613 hasRelatedWork W4292589913 @default.
• W2000588613 hasRelatedWork W2119573293 @default.
• W2000588613 hasVolume "472" @default.

• next