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- W2000591768 abstract "The field of vaccinology began in ignorance of how protection was instilled in vaccine recipients. Today, a greater knowledge of immunology allows us to better understand what is being stimulated by various vaccines that leads to their protective effects: that is, their correlates of protection. Here we describe what is known about the correlates of protection for existing vaccines against a range of different viral diseases and discuss the correlates of protection against disease during natural infection with HIV-1. We will also discuss why it is important to design phase 3 clinical trials of HIV vaccines to determine the correlates of protection for each individual vaccine." @default.
- W2000591768 created "2016-06-24" @default.
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- W2000591768 date "2004-08-01" @default.
- W2000591768 modified "2023-10-18" @default.
- W2000591768 title "Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know" @default.
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- W2000591768 doi "https://doi.org/10.1038/nm0804-806" @default.
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