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• W2000594685 abstract "Cigarette smoking remains the leading cause of preventable death worldwide. However, the efficacy of available first-line therapies remains low, particularly in primary care practice where most smokers seek and receive treatment. These observations reinforce the notion that 'one size fits all' smoking cessation therapies may not be optimal. Therefore, a translational research effort was launched by the Imperial Cancer Research Fund (later Cancer Research UK) General Practice Research Group, who led a decade-long research enterprise that examined the influence of pharmacological hypothesis-driven research into genetic influences on drug response for smoking cessation with transdermal nicotine replacement therapy in general practice.New and previously published smoking cessation genetic association results of 30 candidate gene polymorphisms genotyped for participants in two transdermal nicotine replacement clinical trials based in UK general practices, which employed an intention to analyze approach.By this high bar, one of the polymorphisms (COMT rs4680) was robust to correction for multiple comparisons. Moreover, future research directions are outlined; and lessons learned as well as best-practice models for designing, analyzing, and translating results into clinical practice are proposed.The results and lessons learned from this general practice-based pharmacogenetic research programme provide transportable insights at the transition to the second generation of pharmacogenetic and genomic investigations of smoking cessation and its translation to primary care." @default.
• W2000594685 created "2016-06-24" @default.
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• W2000594685 date "2011-01-25" @default.
• W2000594685 modified "2023-10-18" @default.
• W2000594685 title "Pharmacogenetics of Smoking Cessation in General Practice: Results From the Patch II and Patch in Practice Trials" @default.
• W2000594685 cites W110720742 @default.
• W2000594685 cites W1489636123 @default.
• W2000594685 cites W1584047372 @default.
• W2000594685 cites W1965248635 @default.
• W2000594685 cites W1970128511 @default.
• W2000594685 cites W1970203156 @default.
• W2000594685 cites W1970233695 @default.
• W2000594685 cites W1975898154 @default.
• W2000594685 cites W1979596511 @default.
• W2000594685 cites W1980624172 @default.
• W2000594685 cites W1984282135 @default.
• W2000594685 cites W1988514765 @default.
• W2000594685 cites W1989634408 @default.
• W2000594685 cites W1989901079 @default.
• W2000594685 cites W1994905981 @default.
• W2000594685 cites W1995784890 @default.
• W2000594685 cites W1997343027 @default.
• W2000594685 cites W1999122405 @default.
• W2000594685 cites W1999762185 @default.
• W2000594685 cites W2003786243 @default.
• W2000594685 cites W2011246896 @default.
• W2000594685 cites W2011596780 @default.
• W2000594685 cites W2016161222 @default.
• W2000594685 cites W2017682074 @default.
• W2000594685 cites W2018316956 @default.
• W2000594685 cites W2021450795 @default.
• W2000594685 cites W2022569735 @default.
• W2000594685 cites W2024913341 @default.
• W2000594685 cites W2027653090 @default.
• W2000594685 cites W2035639403 @default.
• W2000594685 cites W2036566504 @default.
• W2000594685 cites W2040095204 @default.
• W2000594685 cites W2041221976 @default.
• W2000594685 cites W2045031661 @default.
• W2000594685 cites W2046545299 @default.
• W2000594685 cites W2047654211 @default.
• W2000594685 cites W2049349701 @default.
• W2000594685 cites W2050054512 @default.
• W2000594685 cites W2051591579 @default.
• W2000594685 cites W2053089324 @default.
• W2000594685 cites W2054856852 @default.
• W2000594685 cites W2059093778 @default.
• W2000594685 cites W2066829527 @default.
• W2000594685 cites W2072955271 @default.
• W2000594685 cites W2074572686 @default.
• W2000594685 cites W2075297244 @default.
• W2000594685 cites W2077723521 @default.
• W2000594685 cites W2078953408 @default.
• W2000594685 cites W2079470785 @default.
• W2000594685 cites W2080089547 @default.
• W2000594685 cites W2083076890 @default.
• W2000594685 cites W2083903511 @default.
• W2000594685 cites W2084663868 @default.
• W2000594685 cites W2090493232 @default.
• W2000594685 cites W2092540250 @default.
• W2000594685 cites W2093946453 @default.
• W2000594685 cites W2100040984 @default.
• W2000594685 cites W2101948727 @default.
• W2000594685 cites W2112107228 @default.
• W2000594685 cites W2114435510 @default.
• W2000594685 cites W2115371904 @default.
• W2000594685 cites W2118061336 @default.
• W2000594685 cites W2119061316 @default.
• W2000594685 cites W2120054127 @default.
• W2000594685 cites W2124289434 @default.
• W2000594685 cites W2125152695 @default.
• W2000594685 cites W2132925324 @default.
• W2000594685 cites W2133880395 @default.
• W2000594685 cites W2135229399 @default.
• W2000594685 cites W2135586912 @default.
• W2000594685 cites W2138330596 @default.
• W2000594685 cites W2138419072 @default.
• W2000594685 cites W2141821529 @default.
• W2000594685 cites W2144943652 @default.
• W2000594685 cites W2151726995 @default.
• W2000594685 cites W2158631567 @default.
• W2000594685 cites W2165398609 @default.
• W2000594685 cites W2168408297 @default.
• W2000594685 cites W2409597498 @default.
• W2000594685 cites W2465795801 @default.
• W2000594685 cites W2475355953 @default.
• W2000594685 cites W330072436 @default.
• W2000594685 cites W4205691790 @default.
• W2000594685 cites W4248784317 @default.
• W2000594685 cites W4249974235 @default.
• W2000594685 cites W4250908461 @default.
• W2000594685 cites W4252153860 @default.

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