Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000605058> ?p ?o ?g. }
- W2000605058 endingPage "188" @default.
- W2000605058 startingPage "181" @default.
- W2000605058 abstract "Internalization of 125I-labelled atrial natriuretic peptide ([ 125I]ANP) by rat adrenal glomerulosa cells in vivo was investigated by means of an ultrastructural autoradiographic approach. One to 30 min after IV injection of [125I]ANP, silver grains were found, at the light microscope level, over all glomerulosa cells; coinjection of 20 micrograms of unlabelled ANP inhibited this binding by 64%. At the electron microscope level, the time-course study indicated maximal silver grain densities in plasma membranes 1 min after IV injection; grains were detected in mitochondria (external membranes and matrix) 2 min after injection, with maximal labelling at 15 min. The cytoplasmic matrix was labelled only 30 min after injection. During the time-course, labelling of nuclei, Golgi apparatus, and lysosomes was minimal. The data suggest that after binding to plasma membranes ANP is rapidly internalized and distributed within glomerulosa cells. The association of radioactivity with mitochondria suggests that ANP may have intracellular sites of action complementary to those on plasma membranes." @default.
- W2000605058 created "2016-06-24" @default.
- W2000605058 creator A5002606558 @default.
- W2000605058 creator A5007735153 @default.
- W2000605058 creator A5015974205 @default.
- W2000605058 creator A5023113978 @default.
- W2000605058 creator A5061040765 @default.
- W2000605058 creator A5077683482 @default.
- W2000605058 date "1989-01-01" @default.
- W2000605058 modified "2023-09-25" @default.
- W2000605058 title "Internalization of atrial natriuretic peptide by adrenal glomerulosa cells" @default.
- W2000605058 cites W159993712 @default.
- W2000605058 cites W1604272930 @default.
- W2000605058 cites W1917292665 @default.
- W2000605058 cites W1964194790 @default.
- W2000605058 cites W1977128451 @default.
- W2000605058 cites W1986114415 @default.
- W2000605058 cites W1988566898 @default.
- W2000605058 cites W2001409353 @default.
- W2000605058 cites W2001466493 @default.
- W2000605058 cites W2007034430 @default.
- W2000605058 cites W2014310907 @default.
- W2000605058 cites W2014944444 @default.
- W2000605058 cites W2016831820 @default.
- W2000605058 cites W2018087126 @default.
- W2000605058 cites W2024494699 @default.
- W2000605058 cites W2042597999 @default.
- W2000605058 cites W2046496618 @default.
- W2000605058 cites W2052097767 @default.
- W2000605058 cites W2057681541 @default.
- W2000605058 cites W2059787491 @default.
- W2000605058 cites W2060338426 @default.
- W2000605058 cites W2061342343 @default.
- W2000605058 cites W2064521512 @default.
- W2000605058 cites W2069916512 @default.
- W2000605058 cites W2071965463 @default.
- W2000605058 cites W2074614053 @default.
- W2000605058 cites W2092850171 @default.
- W2000605058 cites W2095671521 @default.
- W2000605058 cites W2111983335 @default.
- W2000605058 cites W2116962665 @default.
- W2000605058 cites W2157956797 @default.
- W2000605058 cites W2409967665 @default.
- W2000605058 cites W2415130634 @default.
- W2000605058 doi "https://doi.org/10.1111/j.1768-322x.1989.tb00787.x" @default.
- W2000605058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2525411" @default.
- W2000605058 hasPublicationYear "1989" @default.
- W2000605058 type Work @default.
- W2000605058 sameAs 2000605058 @default.
- W2000605058 citedByCount "14" @default.
- W2000605058 countsByYear W20006050582019 @default.
- W2000605058 crossrefType "journal-article" @default.
- W2000605058 hasAuthorship W2000605058A5002606558 @default.
- W2000605058 hasAuthorship W2000605058A5007735153 @default.
- W2000605058 hasAuthorship W2000605058A5015974205 @default.
- W2000605058 hasAuthorship W2000605058A5023113978 @default.
- W2000605058 hasAuthorship W2000605058A5061040765 @default.
- W2000605058 hasAuthorship W2000605058A5077683482 @default.
- W2000605058 hasConcept C119062480 @default.
- W2000605058 hasConcept C126322002 @default.
- W2000605058 hasConcept C134018914 @default.
- W2000605058 hasConcept C139770010 @default.
- W2000605058 hasConcept C1491633281 @default.
- W2000605058 hasConcept C158617107 @default.
- W2000605058 hasConcept C2778069365 @default.
- W2000605058 hasConcept C2778525890 @default.
- W2000605058 hasConcept C2780178468 @default.
- W2000605058 hasConcept C2908929049 @default.
- W2000605058 hasConcept C41625074 @default.
- W2000605058 hasConcept C55493867 @default.
- W2000605058 hasConcept C56191518 @default.
- W2000605058 hasConcept C71315377 @default.
- W2000605058 hasConcept C71924100 @default.
- W2000605058 hasConcept C84393581 @default.
- W2000605058 hasConcept C86803240 @default.
- W2000605058 hasConcept C95444343 @default.
- W2000605058 hasConceptScore W2000605058C119062480 @default.
- W2000605058 hasConceptScore W2000605058C126322002 @default.
- W2000605058 hasConceptScore W2000605058C134018914 @default.
- W2000605058 hasConceptScore W2000605058C139770010 @default.
- W2000605058 hasConceptScore W2000605058C1491633281 @default.
- W2000605058 hasConceptScore W2000605058C158617107 @default.
- W2000605058 hasConceptScore W2000605058C2778069365 @default.
- W2000605058 hasConceptScore W2000605058C2778525890 @default.
- W2000605058 hasConceptScore W2000605058C2780178468 @default.
- W2000605058 hasConceptScore W2000605058C2908929049 @default.
- W2000605058 hasConceptScore W2000605058C41625074 @default.
- W2000605058 hasConceptScore W2000605058C55493867 @default.
- W2000605058 hasConceptScore W2000605058C56191518 @default.
- W2000605058 hasConceptScore W2000605058C71315377 @default.
- W2000605058 hasConceptScore W2000605058C71924100 @default.
- W2000605058 hasConceptScore W2000605058C84393581 @default.
- W2000605058 hasConceptScore W2000605058C86803240 @default.
- W2000605058 hasConceptScore W2000605058C95444343 @default.
- W2000605058 hasIssue "2" @default.
- W2000605058 hasLocation W20006050581 @default.
- W2000605058 hasLocation W20006050582 @default.
- W2000605058 hasOpenAccess W2000605058 @default.