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- W2000606082 endingPage "28" @default.
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- W2000606082 abstract "Regulation of gene expression is a fundamental process in both prokaryotic and eukaryotic organisms. Multiple regulatory mechanisms are in place to control gene expression at the level of transcription, post-transcription and post-translation to maintain optimal RNA and protein expressions in cells. miRNAs (microRNAs) are abundant short 21-23 nt non-coding RNAs that are key regulators of virtually all eukaryotic biological processes. The levels of miRNAs in an organism are crucial for proper development and sustaining optimal cell functions. Therefore the processing and regulation of the processing of these miRNAs are critical. In the present chapter we highlight the most important steps of miRNA processing, describe the functions of key proteins involved in the maturation of miRNAs, and discuss how the generation and the stability of miRNAs are regulated." @default.
- W2000606082 created "2016-06-24" @default.
- W2000606082 creator A5012268284 @default.
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- W2000606082 date "2013-04-30" @default.
- W2000606082 modified "2023-10-12" @default.
- W2000606082 title "Biogenesis and the regulation of the maturation of miRNAs" @default.
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- W2000606082 doi "https://doi.org/10.1042/bse0540017" @default.
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