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- W2000611322 abstract "Economic loss due to viral endothelial cell necrosis of eel (VECNE) of Anguilla japonica is a serious problem for the cultured Japanese eel market. However, the viral genome responsible for VECNE is unknown. We recently developed a rapid determination system for viral nucleic acid sequences (RDV) to determine viral genome sequences. In this study, viral DNA fragments were obtained using RDV, and approximately 15-kbp circular full genome sequences were determined using a next-generation sequencing system, overlapping PCR, and Southern blot analysis. One open reading frame (ORF) was homologous to the large T-antigen of polyomavirus; other ORFs have no homology with any nucleic or amino acid sequences of polyomavirus. Therefore, as this DNA virus might comprise a novel virus family, we provisionally named it Japanese eel endothelial cells-infecting virus (JEECV). JEECV was detected in both naturally and experimentally infected eels, suggesting that JEECV potentially causes VECNE." @default.
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- W2000611322 date "2011-03-01" @default.
- W2000611322 modified "2023-10-17" @default.
- W2000611322 title "Novel DNA virus isolated from samples showing endothelial cell necrosis in the Japanese eel, Anguilla japonica" @default.
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- W2000611322 doi "https://doi.org/10.1016/j.virol.2010.12.057" @default.
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