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- W2000617654 abstract "<h3>BACKGROUND</h3> Oedema is a <i>sine qua non</i>for the diagnosis of kwashiorkor yet the mechanisms leading to oedema remain ill defined. <h3>AIMS</h3> To relate the plasma concentration of radical promoting ‘free’ iron to the degree of oedema in patients with kwashiorkor. <h3>SETTING</h3> University teaching hospital. <h3>PATIENTS</h3> Fifteen children with kwashiorkor, nine of whom had severe and six of whom had a moderate degree of oedema. <h3>METHODS</h3> Plasma ‘free’ iron was measured as bleomycin detectable iron (BDI) and related to severity of oedema and plasma albumin concentration. <h3>RESULTS</h3> BDI was significantly higher in the patients with severe oedema (20.5 <i>v</i> 6.75 μmol/l) whereas the albumin concentrations were similar (16 <i>v</i> 17 g/l). BDI was no longer present in any patients 30 days after admission. <h3>CONCLUSIONS</h3> ‘Free’ circulating iron may contribute to the oedema of kwashiorkor, and its sequestration could hasten recovery and decrease morbidity and mortality." @default.
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- W2000617654 date "1997-01-01" @default.
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- W2000617654 title "Plasma free iron: a possible cause of oedema in kwashiorkor" @default.
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- W2000617654 doi "https://doi.org/10.1136/adc.76.1.54" @default.
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