Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000627160> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2000627160 endingPage "75" @default.
- W2000627160 startingPage "69" @default.
- W2000627160 abstract "To analyse prognostic factors in complete hydatidiform moles using multiple logistic regression analysis.Evaluation of host and tumour related parameters including (a) gestational age, patient age, parity, molar phenotype, grade of proliferation of the tumour and cytological atypia, (b) expression of beta-HCG, EGF, EGFR, TGF-alpha, TGF-beta, IL1-alpha, IL1-beta by immunohistochemistry, (c) serial monitoring of serum beta-HCG levels by ELISA, and (d) lectin binding using jack fruit lectin histochemistry as indices for persisting trophoblastic disease (PTD).Serum beta-HCG levels at 4 weeks, cellular atypia, lectin binding, expression of TGF-alpha and IL1-beta showed highly significant correlation with persistence of the tumour (P<0.001). The sensitivity and specificity at 4 weeks in combination with cytological atypia to identify spontaneously regressing lesions was 100% and those requiring chemotherapeutic intervention was 80%.The concentration of serum beta-HCG 4 weeks post evacuation(<300 mIU/ml) combined with cytological abnormalities could identify nearly 100% of the spontaneously regressing lesions (low risk) and 80% of those needing chemotherapeutic intervention (high risk), thereby suggesting that patients who have a serum beta-HCG at 4 weeks of evacuation <300 mIU/ml with no cytological atypia of the trophoblasts need only be followed up at long intervals, while those having a serum beta-HCG at 4 weeks of evacuation >300 mIU/ml accompanied with cytological atypia of the trophoblasts should be closely followed up." @default.
- W2000627160 created "2016-06-24" @default.
- W2000627160 creator A5027434034 @default.
- W2000627160 creator A5067169879 @default.
- W2000627160 creator A5075089443 @default.
- W2000627160 creator A5079993338 @default.
- W2000627160 creator A5081955946 @default.
- W2000627160 creator A5086975831 @default.
- W2000627160 date "1999-11-01" @default.
- W2000627160 modified "2023-10-16" @default.
- W2000627160 title "A multivariate analysis of prognostic indicators in complete hydatidiform moles (CHM)" @default.
- W2000627160 cites W1585124497 @default.
- W2000627160 cites W178687232 @default.
- W2000627160 cites W1969852055 @default.
- W2000627160 cites W2026771170 @default.
- W2000627160 cites W2027916202 @default.
- W2000627160 cites W2038110109 @default.
- W2000627160 cites W2064253590 @default.
- W2000627160 cites W2070678781 @default.
- W2000627160 cites W2072156172 @default.
- W2000627160 cites W2092255406 @default.
- W2000627160 cites W2415305083 @default.
- W2000627160 cites W2418846688 @default.
- W2000627160 cites W3022691628 @default.
- W2000627160 cites W2487848681 @default.
- W2000627160 doi "https://doi.org/10.1016/s0301-2115(99)00090-1" @default.
- W2000627160 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10579619" @default.
- W2000627160 hasPublicationYear "1999" @default.
- W2000627160 type Work @default.
- W2000627160 sameAs 2000627160 @default.
- W2000627160 citedByCount "9" @default.
- W2000627160 countsByYear W20006271602012 @default.
- W2000627160 crossrefType "journal-article" @default.
- W2000627160 hasAuthorship W2000627160A5027434034 @default.
- W2000627160 hasAuthorship W2000627160A5067169879 @default.
- W2000627160 hasAuthorship W2000627160A5075089443 @default.
- W2000627160 hasAuthorship W2000627160A5079993338 @default.
- W2000627160 hasAuthorship W2000627160A5081955946 @default.
- W2000627160 hasAuthorship W2000627160A5086975831 @default.
- W2000627160 hasConcept C126322002 @default.
- W2000627160 hasConcept C142724271 @default.
- W2000627160 hasConcept C151956035 @default.
- W2000627160 hasConcept C16685009 @default.
- W2000627160 hasConcept C204232928 @default.
- W2000627160 hasConcept C2781283455 @default.
- W2000627160 hasConcept C29456083 @default.
- W2000627160 hasConcept C71924100 @default.
- W2000627160 hasConcept C90924648 @default.
- W2000627160 hasConceptScore W2000627160C126322002 @default.
- W2000627160 hasConceptScore W2000627160C142724271 @default.
- W2000627160 hasConceptScore W2000627160C151956035 @default.
- W2000627160 hasConceptScore W2000627160C16685009 @default.
- W2000627160 hasConceptScore W2000627160C204232928 @default.
- W2000627160 hasConceptScore W2000627160C2781283455 @default.
- W2000627160 hasConceptScore W2000627160C29456083 @default.
- W2000627160 hasConceptScore W2000627160C71924100 @default.
- W2000627160 hasConceptScore W2000627160C90924648 @default.
- W2000627160 hasIssue "1" @default.
- W2000627160 hasLocation W20006271601 @default.
- W2000627160 hasLocation W20006271602 @default.
- W2000627160 hasOpenAccess W2000627160 @default.
- W2000627160 hasPrimaryLocation W20006271601 @default.
- W2000627160 hasRelatedWork W1911438280 @default.
- W2000627160 hasRelatedWork W2058113085 @default.
- W2000627160 hasRelatedWork W2108272515 @default.
- W2000627160 hasRelatedWork W2130894101 @default.
- W2000627160 hasRelatedWork W2161199361 @default.
- W2000627160 hasRelatedWork W2163028754 @default.
- W2000627160 hasRelatedWork W2381576875 @default.
- W2000627160 hasRelatedWork W2502076111 @default.
- W2000627160 hasRelatedWork W2583408542 @default.
- W2000627160 hasRelatedWork W4285518139 @default.
- W2000627160 hasVolume "87" @default.
- W2000627160 isParatext "false" @default.
- W2000627160 isRetracted "false" @default.
- W2000627160 magId "2000627160" @default.
- W2000627160 workType "article" @default.