Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000627657> ?p ?o ?g. }
- W2000627657 endingPage "453" @default.
- W2000627657 startingPage "443" @default.
- W2000627657 abstract "The stereoelectronic considerations and the molecular modeling using an X-ray structure of Rhizomucor miehei lipase suggested that the lipase-catalyzed reactions proceed under the stereoelectronic control. This suggestion was supported by the semiempirical MO (MNDO-PM3) calculations carried out on the imidazole-catalyzed transesterification as a model reaction. The stereoelectronic effect operates at the transition state (TS) more effectively than at the tetrahedral intermediate (THI). The stabilization energy due to the stereoelectronic effect operating at the TS was estimated to be ca. 5 kcal mol−1. The enantioselectivities for 1-phenylethanol, 1-phenyl-2-propanol, and 1-cyclohexylethanol were estimated in terms of the lipase-induced strain caused at the TS. A TS model generally applicable to chiral secondary alcohols is proposed. The kinetic study supported the TS model. The result that the enantioselectivity in the lipase-catalyzed transesterifications arises from the difference in Vmax between the tw..." @default.
- W2000627657 created "2016-06-24" @default.
- W2000627657 creator A5011778824 @default.
- W2000627657 creator A5037470798 @default.
- W2000627657 creator A5045740034 @default.
- W2000627657 creator A5049661518 @default.
- W2000627657 creator A5077175762 @default.
- W2000627657 date "1998-02-01" @default.
- W2000627657 modified "2023-10-14" @default.
- W2000627657 title "Origin of the Enantioselectivity of Lipases Explained by a Stereo-Sensing Mechanism Operative at the Transition State" @default.
- W2000627657 cites W1494306575 @default.
- W2000627657 cites W1584350616 @default.
- W2000627657 cites W1965451226 @default.
- W2000627657 cites W1969224656 @default.
- W2000627657 cites W1969973806 @default.
- W2000627657 cites W1973137228 @default.
- W2000627657 cites W1974807891 @default.
- W2000627657 cites W1975592007 @default.
- W2000627657 cites W1976951969 @default.
- W2000627657 cites W1978754543 @default.
- W2000627657 cites W1981542683 @default.
- W2000627657 cites W1984634516 @default.
- W2000627657 cites W1986839844 @default.
- W2000627657 cites W1987470484 @default.
- W2000627657 cites W1987995046 @default.
- W2000627657 cites W1989907026 @default.
- W2000627657 cites W1996293431 @default.
- W2000627657 cites W2006184477 @default.
- W2000627657 cites W2012176370 @default.
- W2000627657 cites W2015484843 @default.
- W2000627657 cites W2016912149 @default.
- W2000627657 cites W2017693501 @default.
- W2000627657 cites W2022245684 @default.
- W2000627657 cites W2023513562 @default.
- W2000627657 cites W2024868983 @default.
- W2000627657 cites W2030795605 @default.
- W2000627657 cites W2032737762 @default.
- W2000627657 cites W2033495093 @default.
- W2000627657 cites W2036414218 @default.
- W2000627657 cites W2038023483 @default.
- W2000627657 cites W2038671143 @default.
- W2000627657 cites W2048069826 @default.
- W2000627657 cites W2052105542 @default.
- W2000627657 cites W2063168832 @default.
- W2000627657 cites W2067431380 @default.
- W2000627657 cites W2068708042 @default.
- W2000627657 cites W2070598555 @default.
- W2000627657 cites W2072313629 @default.
- W2000627657 cites W2075266643 @default.
- W2000627657 cites W2078247260 @default.
- W2000627657 cites W2086404667 @default.
- W2000627657 cites W2087183253 @default.
- W2000627657 cites W2088668995 @default.
- W2000627657 cites W2094028951 @default.
- W2000627657 cites W2110989154 @default.
- W2000627657 cites W2111310989 @default.
- W2000627657 cites W2123004458 @default.
- W2000627657 cites W2127336290 @default.
- W2000627657 cites W2141424157 @default.
- W2000627657 cites W2145130697 @default.
- W2000627657 cites W2155358697 @default.
- W2000627657 cites W2167815611 @default.
- W2000627657 cites W2205582644 @default.
- W2000627657 cites W2950209999 @default.
- W2000627657 cites W2950633309 @default.
- W2000627657 cites W2950847729 @default.
- W2000627657 cites W2952390066 @default.
- W2000627657 cites W2952741691 @default.
- W2000627657 cites W2953207138 @default.
- W2000627657 cites W4240620708 @default.
- W2000627657 cites W4240660828 @default.
- W2000627657 doi "https://doi.org/10.1246/bcsj.71.443" @default.
- W2000627657 hasPublicationYear "1998" @default.
- W2000627657 type Work @default.
- W2000627657 sameAs 2000627657 @default.
- W2000627657 citedByCount "75" @default.
- W2000627657 countsByYear W20006276572012 @default.
- W2000627657 countsByYear W20006276572014 @default.
- W2000627657 countsByYear W20006276572015 @default.
- W2000627657 countsByYear W20006276572016 @default.
- W2000627657 countsByYear W20006276572017 @default.
- W2000627657 countsByYear W20006276572018 @default.
- W2000627657 countsByYear W20006276572021 @default.
- W2000627657 countsByYear W20006276572023 @default.
- W2000627657 crossrefType "journal-article" @default.
- W2000627657 hasAuthorship W2000627657A5011778824 @default.
- W2000627657 hasAuthorship W2000627657A5037470798 @default.
- W2000627657 hasAuthorship W2000627657A5045740034 @default.
- W2000627657 hasAuthorship W2000627657A5049661518 @default.
- W2000627657 hasAuthorship W2000627657A5077175762 @default.
- W2000627657 hasConcept C104317684 @default.
- W2000627657 hasConcept C11413529 @default.
- W2000627657 hasConcept C121332964 @default.
- W2000627657 hasConcept C147597530 @default.
- W2000627657 hasConcept C159467904 @default.
- W2000627657 hasConcept C161790260 @default.
- W2000627657 hasConcept C178790620 @default.
- W2000627657 hasConcept C185592680 @default.