FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000631736> ?p ?o ?g. }

• W2000631736 endingPage "1361" @default.
• W2000631736 startingPage "1355" @default.
• W2000631736 abstract "The T cell antigen receptor complexes expressed on αβ and γδ T cells differ not only in their respective clonotypic heterodimers but also in the subunit composition of their CD3 complexes. The γδ T cell receptors (TCRs) expressed on ex vivo γδ T cells lack CD3δ, whereas αβ TCRs contain CD3δ. While this result correlates with the phenotype of CD3δ−/− mice, in which γδ T cell development is unaffected, it is inconsistent with the results of previous studies reporting that CD3δ is a component of the γδ TCR. Since earlier studies examined the subunit composition of γδ TCRs expressed on activated and expanded peripheral γδ T cells or γδ TCR+ intestinal intraepithelial lymphocytes, we hypothesized that activation and expansion may lead to changes in the CD3 subunit composition of the γδ TCR. Here, we report that activation and expansion do in fact result in the inclusion of a protein, comparable in mass and mobility to CD3δ, in the γδ TCR. Further analyses revealed that this protein is not CD3δ, but instead is a differentially glycosylated form of CD3γ. These results provide further evidence for a major difference in the subunit composition of αβ- and γδ TCR complexes and raise the possibility that modification of CD3γ may have important functional consequences in activated γδ T cells." @default.
• W2000631736 created "2016-06-24" @default.
• W2000631736 creator A5003776075 @default.
• W2000631736 creator A5043853595 @default.
• W2000631736 creator A5045158744 @default.
• W2000631736 creator A5051146159 @default.
• W2000631736 creator A5052571661 @default.
• W2000631736 creator A5056712319 @default.
• W2000631736 date "2002-11-11" @default.
• W2000631736 modified "2023-10-17" @default.
• W2000631736 title "Activation-induced Modification in the CD3 Complex of the γδ T Cell Receptor" @default.
• W2000631736 cites W1541131175 @default.
• W2000631736 cites W1815213720 @default.
• W2000631736 cites W1851182718 @default.
• W2000631736 cites W1907736024 @default.
• W2000631736 cites W1981563612 @default.
• W2000631736 cites W2014863755 @default.
• W2000631736 cites W2021820035 @default.
• W2000631736 cites W2034699474 @default.
• W2000631736 cites W2036458764 @default.
• W2000631736 cites W2037821829 @default.
• W2000631736 cites W2040512118 @default.
• W2000631736 cites W2042761559 @default.
• W2000631736 cites W2043521345 @default.
• W2000631736 cites W2050356515 @default.
• W2000631736 cites W2059508724 @default.
• W2000631736 cites W2073762107 @default.
• W2000631736 cites W2080380130 @default.
• W2000631736 cites W2095076160 @default.
• W2000631736 cites W2098952209 @default.
• W2000631736 cites W2111536196 @default.
• W2000631736 cites W2114951959 @default.
• W2000631736 cites W2140769164 @default.
• W2000631736 cites W2151206902 @default.
• W2000631736 cites W2152030716 @default.
• W2000631736 cites W2157039288 @default.
• W2000631736 doi "https://doi.org/10.1084/jem.20021196" @default.
• W2000631736 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2193986" @default.
• W2000631736 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12438426" @default.
• W2000631736 hasPublicationYear "2002" @default.
• W2000631736 type Work @default.
• W2000631736 sameAs 2000631736 @default.
• W2000631736 citedByCount "23" @default.
• W2000631736 countsByYear W20006317362016 @default.
• W2000631736 countsByYear W20006317362018 @default.
• W2000631736 countsByYear W20006317362020 @default.
• W2000631736 countsByYear W20006317362021 @default.
• W2000631736 crossrefType "journal-article" @default.
• W2000631736 hasAuthorship W2000631736A5003776075 @default.
• W2000631736 hasAuthorship W2000631736A5043853595 @default.
• W2000631736 hasAuthorship W2000631736A5045158744 @default.
• W2000631736 hasAuthorship W2000631736A5051146159 @default.
• W2000631736 hasAuthorship W2000631736A5052571661 @default.
• W2000631736 hasAuthorship W2000631736A5056712319 @default.
• W2000631736 hasBestOaLocation W20006317361 @default.
• W2000631736 hasConcept C104292427 @default.
• W2000631736 hasConcept C104317684 @default.
• W2000631736 hasConcept C114684123 @default.
• W2000631736 hasConcept C147483822 @default.
• W2000631736 hasConcept C153911025 @default.
• W2000631736 hasConcept C167672396 @default.
• W2000631736 hasConcept C170493617 @default.
• W2000631736 hasConcept C19317047 @default.
• W2000631736 hasConcept C203014093 @default.
• W2000631736 hasConcept C2776090121 @default.
• W2000631736 hasConcept C55493867 @default.
• W2000631736 hasConcept C86803240 @default.
• W2000631736 hasConcept C8891405 @default.
• W2000631736 hasConcept C95444343 @default.
• W2000631736 hasConceptScore W2000631736C104292427 @default.
• W2000631736 hasConceptScore W2000631736C104317684 @default.
• W2000631736 hasConceptScore W2000631736C114684123 @default.
• W2000631736 hasConceptScore W2000631736C147483822 @default.
• W2000631736 hasConceptScore W2000631736C153911025 @default.
• W2000631736 hasConceptScore W2000631736C167672396 @default.
• W2000631736 hasConceptScore W2000631736C170493617 @default.
• W2000631736 hasConceptScore W2000631736C19317047 @default.
• W2000631736 hasConceptScore W2000631736C203014093 @default.
• W2000631736 hasConceptScore W2000631736C2776090121 @default.
• W2000631736 hasConceptScore W2000631736C55493867 @default.
• W2000631736 hasConceptScore W2000631736C86803240 @default.
• W2000631736 hasConceptScore W2000631736C8891405 @default.
• W2000631736 hasConceptScore W2000631736C95444343 @default.
• W2000631736 hasIssue "10" @default.
• W2000631736 hasLocation W20006317361 @default.
• W2000631736 hasLocation W20006317362 @default.
• W2000631736 hasLocation W20006317363 @default.
• W2000631736 hasLocation W20006317364 @default.
• W2000631736 hasOpenAccess W2000631736 @default.
• W2000631736 hasPrimaryLocation W20006317361 @default.
• W2000631736 hasRelatedWork W138661586 @default.
• W2000631736 hasRelatedWork W1518741832 @default.
• W2000631736 hasRelatedWork W2025159433 @default.
• W2000631736 hasRelatedWork W2042173550 @default.
• W2000631736 hasRelatedWork W2066661529 @default.
• W2000631736 hasRelatedWork W2083598728 @default.
• W2000631736 hasRelatedWork W2093146731 @default.
• W2000631736 hasRelatedWork W2747317233 @default.

• next