Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000633182> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2000633182 endingPage "152" @default.
- W2000633182 startingPage "147" @default.
- W2000633182 abstract "IL-12 priming plays an important role in stimulation of CD8+ effector T cells and development of CD8+ memory T (Tm) cells. However, the functional alteration of CD8+ Tm cells developed in the absence of IL-12 priming is elusive. In this study, we investigated the capacity of secondary expansion of CD8+ Tm cells developed from transgenic OT I CD8+ T cells. The latter cells were in vitro and in vivo stimulated by ovalbumin (OVA)-pulsed dendritic cells [DCOVA and (IL-12-/-)DCOVA] derived from wild-type C57BL/6 and IL-12 gene knockout mice, respectively. We demonstrated that IL-12 priming is important not only in CD8+ T cell clonal expansion, but also in generation of CD8+ Tm cells with the capacity of secondary expansion upon antigen re-encounter. However, IL-12 signaling is not involved in CD8+ Tm cell survival and recall responses. Therefore, this study provides useful information for vaccine design and development." @default.
- W2000633182 created "2016-06-24" @default.
- W2000633182 creator A5014500064 @default.
- W2000633182 creator A5015771286 @default.
- W2000633182 creator A5026627389 @default.
- W2000633182 creator A5071965865 @default.
- W2000633182 creator A5075248303 @default.
- W2000633182 date "2008-04-01" @default.
- W2000633182 modified "2023-09-25" @default.
- W2000633182 title "Defect of CD8+ Memory T Cells Developed in Absence of IL-12 Priming for Secondary Expansion" @default.
- W2000633182 doi "https://doi.org/10.1038/cmi.2008.18" @default.
- W2000633182 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4651243" @default.
- W2000633182 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18445345" @default.
- W2000633182 hasPublicationYear "2008" @default.
- W2000633182 type Work @default.
- W2000633182 sameAs 2000633182 @default.
- W2000633182 citedByCount "11" @default.
- W2000633182 countsByYear W20006331822012 @default.
- W2000633182 countsByYear W20006331822013 @default.
- W2000633182 countsByYear W20006331822015 @default.
- W2000633182 countsByYear W20006331822021 @default.
- W2000633182 countsByYear W20006331822022 @default.
- W2000633182 countsByYear W20006331822023 @default.
- W2000633182 crossrefType "journal-article" @default.
- W2000633182 hasAuthorship W2000633182A5014500064 @default.
- W2000633182 hasAuthorship W2000633182A5015771286 @default.
- W2000633182 hasAuthorship W2000633182A5026627389 @default.
- W2000633182 hasAuthorship W2000633182A5071965865 @default.
- W2000633182 hasAuthorship W2000633182A5075248303 @default.
- W2000633182 hasBestOaLocation W20006331821 @default.
- W2000633182 hasConcept C100701293 @default.
- W2000633182 hasConcept C102230213 @default.
- W2000633182 hasConcept C104317684 @default.
- W2000633182 hasConcept C129374314 @default.
- W2000633182 hasConcept C147483822 @default.
- W2000633182 hasConcept C149532602 @default.
- W2000633182 hasConcept C154317977 @default.
- W2000633182 hasConcept C167672396 @default.
- W2000633182 hasConcept C202751555 @default.
- W2000633182 hasConcept C203014093 @default.
- W2000633182 hasConcept C54355233 @default.
- W2000633182 hasConcept C59822182 @default.
- W2000633182 hasConcept C81444415 @default.
- W2000633182 hasConcept C86803240 @default.
- W2000633182 hasConcept C95444343 @default.
- W2000633182 hasConceptScore W2000633182C100701293 @default.
- W2000633182 hasConceptScore W2000633182C102230213 @default.
- W2000633182 hasConceptScore W2000633182C104317684 @default.
- W2000633182 hasConceptScore W2000633182C129374314 @default.
- W2000633182 hasConceptScore W2000633182C147483822 @default.
- W2000633182 hasConceptScore W2000633182C149532602 @default.
- W2000633182 hasConceptScore W2000633182C154317977 @default.
- W2000633182 hasConceptScore W2000633182C167672396 @default.
- W2000633182 hasConceptScore W2000633182C202751555 @default.
- W2000633182 hasConceptScore W2000633182C203014093 @default.
- W2000633182 hasConceptScore W2000633182C54355233 @default.
- W2000633182 hasConceptScore W2000633182C59822182 @default.
- W2000633182 hasConceptScore W2000633182C81444415 @default.
- W2000633182 hasConceptScore W2000633182C86803240 @default.
- W2000633182 hasConceptScore W2000633182C95444343 @default.
- W2000633182 hasIssue "2" @default.
- W2000633182 hasLocation W20006331821 @default.
- W2000633182 hasLocation W20006331822 @default.
- W2000633182 hasLocation W20006331823 @default.
- W2000633182 hasLocation W20006331824 @default.
- W2000633182 hasOpenAccess W2000633182 @default.
- W2000633182 hasPrimaryLocation W20006331821 @default.
- W2000633182 hasRelatedWork W1599518596 @default.
- W2000633182 hasRelatedWork W1968028452 @default.
- W2000633182 hasRelatedWork W198401270 @default.
- W2000633182 hasRelatedWork W1989812836 @default.
- W2000633182 hasRelatedWork W2021750859 @default.
- W2000633182 hasRelatedWork W2079087426 @default.
- W2000633182 hasRelatedWork W2138290228 @default.
- W2000633182 hasRelatedWork W2466063666 @default.
- W2000633182 hasRelatedWork W2502297276 @default.
- W2000633182 hasRelatedWork W4379615303 @default.
- W2000633182 hasVolume "5" @default.
- W2000633182 isParatext "false" @default.
- W2000633182 isRetracted "false" @default.
- W2000633182 magId "2000633182" @default.
- W2000633182 workType "article" @default.