FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000638302> ?p ?o ?g. }

• W2000638302 endingPage "322" @default.
• W2000638302 startingPage "317" @default.
• W2000638302 abstract "Background Thin film nitinol (TFN) is a novel material with which to cover stents for the treatment of a wide range of vascular disease processes. This study aimed to show that TFN, if treated to produce a super hydrophilic surface, significantly reduces platelet adhesion, potentially rendering covered stents more resistant to thrombosis compared to commercially available materials. Materials and Methods TFN was fabricated using a sputter deposition process to produce a 5-μ thin film of uniform thickness. TFN then underwent a surface treatment process to create a super hydrophilic layer. Platelet adhesion studies compared surface treated TFN (S-TFN) to untreated TFN, polytetrafluoroethylene, Dacron, and bulk nitinol. In vivo swine studies examined the placement of an S-TFN covered stent in a 3.5 mm diameter external iliac artery. Angiography confirmed placement, and repeat angiography was performed at 2 wk followed by post mortem histopathology. Results S-TFN significantly reduced platelet adhesion without any evidence of aggregation compared with all materials studied (P < 0.05). Furthermore, in vivo swine studies demonstrated complete patency of the S-TFN covered stent at 2 wk. Post mortem histopathology showed rapid endothelialization of the S-TFN without excessive neointimal hyperplasia. Conclusions These results demonstrate that S-TFN significantly reduces platelet adhesion and aggregation compared with commercially available endograft materials. Furthermore, the hydrophilic surface may confer thromboresistance in vivo, suggesting that S-TFN is a possible superior material for covering stents. Thin film nitinol (TFN) is a novel material with which to cover stents for the treatment of a wide range of vascular disease processes. This study aimed to show that TFN, if treated to produce a super hydrophilic surface, significantly reduces platelet adhesion, potentially rendering covered stents more resistant to thrombosis compared to commercially available materials. TFN was fabricated using a sputter deposition process to produce a 5-μ thin film of uniform thickness. TFN then underwent a surface treatment process to create a super hydrophilic layer. Platelet adhesion studies compared surface treated TFN (S-TFN) to untreated TFN, polytetrafluoroethylene, Dacron, and bulk nitinol. In vivo swine studies examined the placement of an S-TFN covered stent in a 3.5 mm diameter external iliac artery. Angiography confirmed placement, and repeat angiography was performed at 2 wk followed by post mortem histopathology. S-TFN significantly reduced platelet adhesion without any evidence of aggregation compared with all materials studied (P < 0.05). Furthermore, in vivo swine studies demonstrated complete patency of the S-TFN covered stent at 2 wk. Post mortem histopathology showed rapid endothelialization of the S-TFN without excessive neointimal hyperplasia. These results demonstrate that S-TFN significantly reduces platelet adhesion and aggregation compared with commercially available endograft materials. Furthermore, the hydrophilic surface may confer thromboresistance in vivo, suggesting that S-TFN is a possible superior material for covering stents." @default.
• W2000638302 created "2016-06-24" @default.
• W2000638302 creator A5001891256 @default.
• W2000638302 creator A5006436052 @default.
• W2000638302 creator A5037581428 @default.
• W2000638302 creator A5048131297 @default.
• W2000638302 creator A5052867512 @default.
• W2000638302 creator A5056608330 @default.
• W2000638302 creator A5067194248 @default.
• W2000638302 date "2011-11-01" @default.
• W2000638302 modified "2023-10-16" @default.
• W2000638302 title "Super Hydrophilic Thin Film Nitinol Demonstrates Reduced Platelet Adhesion Compared with Commercially Available Endograft Materials" @default.
• W2000638302 cites W1608595618 @default.
• W2000638302 cites W1964595973 @default.
• W2000638302 cites W1988338662 @default.
• W2000638302 cites W1997848759 @default.
• W2000638302 cites W2001536458 @default.
• W2000638302 cites W2014277286 @default.
• W2000638302 cites W2015741864 @default.
• W2000638302 cites W2052453255 @default.
• W2000638302 cites W2052965506 @default.
• W2000638302 cites W2058388757 @default.
• W2000638302 cites W2062283920 @default.
• W2000638302 cites W2093072668 @default.
• W2000638302 cites W2109117281 @default.
• W2000638302 cites W2121456889 @default.
• W2000638302 cites W2124289669 @default.
• W2000638302 cites W2144985796 @default.
• W2000638302 cites W2147968938 @default.
• W2000638302 cites W2472248045 @default.
• W2000638302 cites W4241860938 @default.
• W2000638302 cites W1983310984 @default.
• W2000638302 doi "https://doi.org/10.1016/j.jss.2010.01.014" @default.
• W2000638302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20451925" @default.
• W2000638302 hasPublicationYear "2011" @default.
• W2000638302 type Work @default.
• W2000638302 sameAs 2000638302 @default.
• W2000638302 citedByCount "26" @default.
• W2000638302 countsByYear W20006383022012 @default.
• W2000638302 countsByYear W20006383022014 @default.
• W2000638302 countsByYear W20006383022015 @default.
• W2000638302 countsByYear W20006383022016 @default.
• W2000638302 countsByYear W20006383022017 @default.
• W2000638302 countsByYear W20006383022018 @default.
• W2000638302 countsByYear W20006383022020 @default.
• W2000638302 countsByYear W20006383022021 @default.
• W2000638302 countsByYear W20006383022022 @default.
• W2000638302 crossrefType "journal-article" @default.
• W2000638302 hasAuthorship W2000638302A5001891256 @default.
• W2000638302 hasAuthorship W2000638302A5006436052 @default.
• W2000638302 hasAuthorship W2000638302A5037581428 @default.
• W2000638302 hasAuthorship W2000638302A5048131297 @default.
• W2000638302 hasAuthorship W2000638302A5052867512 @default.
• W2000638302 hasAuthorship W2000638302A5056608330 @default.
• W2000638302 hasAuthorship W2000638302A5067194248 @default.
• W2000638302 hasConcept C126322002 @default.
• W2000638302 hasConcept C126838900 @default.
• W2000638302 hasConcept C136229726 @default.
• W2000638302 hasConcept C141071460 @default.
• W2000638302 hasConcept C142724271 @default.
• W2000638302 hasConcept C159985019 @default.
• W2000638302 hasConcept C192562407 @default.
• W2000638302 hasConcept C2777339539 @default.
• W2000638302 hasConcept C2778283817 @default.
• W2000638302 hasConcept C2778583881 @default.
• W2000638302 hasConcept C2780009322 @default.
• W2000638302 hasConcept C2780643987 @default.
• W2000638302 hasConcept C2993802102 @default.
• W2000638302 hasConcept C544855455 @default.
• W2000638302 hasConcept C71924100 @default.
• W2000638302 hasConcept C84416704 @default.
• W2000638302 hasConcept C89560881 @default.
• W2000638302 hasConceptScore W2000638302C126322002 @default.
• W2000638302 hasConceptScore W2000638302C126838900 @default.
• W2000638302 hasConceptScore W2000638302C136229726 @default.
• W2000638302 hasConceptScore W2000638302C141071460 @default.
• W2000638302 hasConceptScore W2000638302C142724271 @default.
• W2000638302 hasConceptScore W2000638302C159985019 @default.
• W2000638302 hasConceptScore W2000638302C192562407 @default.
• W2000638302 hasConceptScore W2000638302C2777339539 @default.
• W2000638302 hasConceptScore W2000638302C2778283817 @default.
• W2000638302 hasConceptScore W2000638302C2778583881 @default.
• W2000638302 hasConceptScore W2000638302C2780009322 @default.
• W2000638302 hasConceptScore W2000638302C2780643987 @default.
• W2000638302 hasConceptScore W2000638302C2993802102 @default.
• W2000638302 hasConceptScore W2000638302C544855455 @default.
• W2000638302 hasConceptScore W2000638302C71924100 @default.
• W2000638302 hasConceptScore W2000638302C84416704 @default.
• W2000638302 hasConceptScore W2000638302C89560881 @default.
• W2000638302 hasIssue "1" @default.
• W2000638302 hasLocation W20006383021 @default.
• W2000638302 hasLocation W20006383022 @default.
• W2000638302 hasOpenAccess W2000638302 @default.
• W2000638302 hasPrimaryLocation W20006383021 @default.
• W2000638302 hasRelatedWork W1932675113 @default.
• W2000638302 hasRelatedWork W1998002261 @default.
• W2000638302 hasRelatedWork W2077883450 @default.
• W2000638302 hasRelatedWork W2078694824 @default.

• next