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- W2000642258 abstract "Abstract In the present study, we investigated the acetylcholinesterase (AChE) inhibitory activity of the ethanolic extracts of a number of mushroom species growing in Turkey, including mainly Polyporus species ( Polyporus gilvus , Polyporus sulphureus , Polyporus annosus , Polyporus radiatus , Polyporus pinicola , Polyporus volvatus , Polyporus fomentarius , Polyporus stevenii , Polyporus badius ), as well as Cantharellus cibarius , Lactarius deliciosus , and Trametes versicolor . The analyses were carried out using the spectrophotometric method of Ellman in ELISA microplate reader at 500 μg/ml. Since Alzheimer's disease (AD) is associated with oxidative degeneration of cells, several methods of antioxidant activity were applied to the mushroom extracts such as 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, ferrous ion-chelating effect, ferric-reducing antioxidant power (FRAP), and beta-carotene bleaching tests. Total phenol contents of the extracts were also determined by Folin–Ciocalteu reagent. In anti-AChE assay, the most active one was P. sulphureus having 31.44% of inhibition. P. voluatus showed the best scavenging effect against DPPH, while all of the extracts exerted low capacity in chelating ferrous ions and reducing ferric ion." @default.
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- W2000642258 date "2011-05-01" @default.
- W2000642258 modified "2023-10-18" @default.
- W2000642258 title "Determination of total phenol content, antioxidant activity and acetylcholinesterase inhibition in selected mushrooms from Turkey" @default.
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- W2000642258 doi "https://doi.org/10.1016/j.jfca.2010.11.005" @default.
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