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- W2000642931 abstract "Summary. A double-blind, placebo-controlled trial was conducted to assess the maternal and fetal endocrine effects of epostane, an inhibitor of progesterone synthesis, in mid-pregnancy. Although present in the maternal circulation, epostane was not detected in cord blood or amniotic fluid. Maternal and fetal progesterone levels fell by 80% and 95% respectively with maintenance of the fetal arterio-venous difference while oestradiol and aldosterone levels were affected to a lesser extent. The mechanism of 3-beta hydroxy steroid dehydrogenase suppression and the relation between fetal and maternal progesterone levels are discussed." @default.
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- W2000642931 date "1988-06-01" @default.
- W2000642931 modified "2023-09-26" @default.
- W2000642931 title "The effect of epostane, a 3-beta hydroxy steroid dehydrogenase inhibitor, on maternal and fetal steroid levels during mid-gestation" @default.
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- W2000642931 doi "https://doi.org/10.1111/j.1471-0528.1988.tb09490.x" @default.
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