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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000643387> ?p ?o ?g. }

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• W2000643387 abstract "In an effort to develop potent and selective inhibitors toward ACAT2, structure–activity relationship studies were carried out using derivatives based on pyripyropene A (PPPA, 1). We have successfully developed novel PPPA derivatives with a 7-O-substituted benzoyl substituent that significantly exhibit more potent ACAT2 inhibitory activity and higher ACAT2 isozyme selectivity than 1." @default.
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• W2000643387 date "2013-03-01" @default.
• W2000643387 modified "2023-10-18" @default.
• W2000643387 title "Synthesis and structure–activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: Part 1" @default.
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• W2000643387 doi "https://doi.org/10.1016/j.bmcl.2012.12.099" @default.
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