Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000644898> ?p ?o ?g. }
- W2000644898 endingPage "719" @default.
- W2000644898 startingPage "707" @default.
- W2000644898 abstract "We synthesized a new 2-methyl derivative of wyosine using a multistep procedure starting from guanosine. We examined different synthetic paths and optimized the conditions for each step. Based on MD calculations and analysis of the (3) J (HH) and J (C1'H1') of the ribose moiety, we discovered that the sugar part adopted conformation specific for the East region rarely occurring in solution. This unusual conformational preference is probably due to steric repulsions between the methyl group at position 2 and the 5'-CH(2)OH group. We observed that N-glycosidic bond stability weakened 14-fold upon the introduction of the methyl group in position 2 compared with wyosine." @default.
- W2000644898 created "2016-06-24" @default.
- W2000644898 creator A5018487426 @default.
- W2000644898 creator A5031107638 @default.
- W2000644898 creator A5058912256 @default.
- W2000644898 creator A5070926398 @default.
- W2000644898 date "2012-10-01" @default.
- W2000644898 modified "2023-10-16" @default.
- W2000644898 title "2-Methylwyosine, a Nucleoside With Restricted Anti Conformation in the East Region Enforced by Nucleobase Moiety Modification: Synthesis and Conformational Analysis by NMR and Molecular Dynamics" @default.
- W2000644898 cites W1970320320 @default.
- W2000644898 cites W1971702269 @default.
- W2000644898 cites W1972225177 @default.
- W2000644898 cites W1974067623 @default.
- W2000644898 cites W1976607125 @default.
- W2000644898 cites W1992328469 @default.
- W2000644898 cites W1993826178 @default.
- W2000644898 cites W1997637365 @default.
- W2000644898 cites W1999249940 @default.
- W2000644898 cites W2000480344 @default.
- W2000644898 cites W2004953078 @default.
- W2000644898 cites W2016129312 @default.
- W2000644898 cites W2018032976 @default.
- W2000644898 cites W2023073412 @default.
- W2000644898 cites W2027103482 @default.
- W2000644898 cites W2033630082 @default.
- W2000644898 cites W2043738469 @default.
- W2000644898 cites W2049679126 @default.
- W2000644898 cites W2051435733 @default.
- W2000644898 cites W2053384992 @default.
- W2000644898 cites W2061543485 @default.
- W2000644898 cites W2061822610 @default.
- W2000644898 cites W2061847800 @default.
- W2000644898 cites W2063834373 @default.
- W2000644898 cites W2065293630 @default.
- W2000644898 cites W2068835105 @default.
- W2000644898 cites W2074090001 @default.
- W2000644898 cites W2079020386 @default.
- W2000644898 cites W2080161964 @default.
- W2000644898 cites W2085013279 @default.
- W2000644898 cites W2101386363 @default.
- W2000644898 cites W2124353773 @default.
- W2000644898 cites W2130880846 @default.
- W2000644898 cites W2142189265 @default.
- W2000644898 cites W2150409129 @default.
- W2000644898 cites W2155060633 @default.
- W2000644898 cites W2162759883 @default.
- W2000644898 cites W2167313323 @default.
- W2000644898 cites W2322330924 @default.
- W2000644898 cites W2482664936 @default.
- W2000644898 cites W2520032022 @default.
- W2000644898 cites W2949839125 @default.
- W2000644898 doi "https://doi.org/10.1080/15257770.2012.724133" @default.
- W2000644898 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23067123" @default.
- W2000644898 hasPublicationYear "2012" @default.
- W2000644898 type Work @default.
- W2000644898 sameAs 2000644898 @default.
- W2000644898 citedByCount "1" @default.
- W2000644898 countsByYear W20006448982016 @default.
- W2000644898 crossrefType "journal-article" @default.
- W2000644898 hasAuthorship W2000644898A5018487426 @default.
- W2000644898 hasAuthorship W2000644898A5031107638 @default.
- W2000644898 hasAuthorship W2000644898A5058912256 @default.
- W2000644898 hasAuthorship W2000644898A5070926398 @default.
- W2000644898 hasConcept C147597530 @default.
- W2000644898 hasConcept C150487720 @default.
- W2000644898 hasConcept C178790620 @default.
- W2000644898 hasConcept C181199279 @default.
- W2000644898 hasConcept C185592680 @default.
- W2000644898 hasConcept C201194858 @default.
- W2000644898 hasConcept C2776543447 @default.
- W2000644898 hasConcept C2776568683 @default.
- W2000644898 hasConcept C2777995097 @default.
- W2000644898 hasConcept C2778565081 @default.
- W2000644898 hasConcept C2779461342 @default.
- W2000644898 hasConcept C2781311116 @default.
- W2000644898 hasConcept C552990157 @default.
- W2000644898 hasConcept C55493867 @default.
- W2000644898 hasConcept C59593255 @default.
- W2000644898 hasConcept C61234307 @default.
- W2000644898 hasConcept C71240020 @default.
- W2000644898 hasConceptScore W2000644898C147597530 @default.
- W2000644898 hasConceptScore W2000644898C150487720 @default.
- W2000644898 hasConceptScore W2000644898C178790620 @default.
- W2000644898 hasConceptScore W2000644898C181199279 @default.
- W2000644898 hasConceptScore W2000644898C185592680 @default.
- W2000644898 hasConceptScore W2000644898C201194858 @default.
- W2000644898 hasConceptScore W2000644898C2776543447 @default.
- W2000644898 hasConceptScore W2000644898C2776568683 @default.
- W2000644898 hasConceptScore W2000644898C2777995097 @default.
- W2000644898 hasConceptScore W2000644898C2778565081 @default.
- W2000644898 hasConceptScore W2000644898C2779461342 @default.
- W2000644898 hasConceptScore W2000644898C2781311116 @default.
- W2000644898 hasConceptScore W2000644898C552990157 @default.
- W2000644898 hasConceptScore W2000644898C55493867 @default.
- W2000644898 hasConceptScore W2000644898C59593255 @default.
- W2000644898 hasConceptScore W2000644898C61234307 @default.
- W2000644898 hasConceptScore W2000644898C71240020 @default.
- W2000644898 hasIssue "10" @default.