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- W2000646928 abstract "Studies on vertical transmission of HIV have not considered the possible influence of paternal HIV infection. Fetal infection could result from integration of HIV in the sperm, but evidence for this is still controversial.1 Integration of HIV may occur in only a few sperm or reduce their fertility, which would make direct transmission from the father rare. No birth of an HIV positive infant to an uninfected mother has been reported. Furthermore, the insemination of HIV negative women with the processed semen of their HIV positive partners has led to non-infected babies.2Paternal HIV infection could influence vertical transmission by other mechanisms. Infected men shed cell free HIV and cell associated HIV in their semen.3 Unprotected intercourse during pregnancy would result in an unknown quantity of infected semen being repeatedly deposited inside the vagina, putting babies who are delivered by the vaginal route at increased risk of infection. We investigated whether paternal HIV increase the risk of vertical transmission.Children born since 1986 to women known to be HIV positive were enrolled in a collaborative study and followed up from birth. We reviewed 201 mothers and their 205 infants …" @default.
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- W2000646928 date "1994-02-12" @default.
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- W2000646928 title "Paternal HIV infection and transfer of HIV from mother to fetus" @default.
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- W2000646928 cites W2111103957 @default.
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- W2000646928 doi "https://doi.org/10.1136/bmj.308.6926.453" @default.
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