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- W2000647623 abstract "The formation of specific antigen, defined as material of large molecular weight, which will combine with T1 antibody, by T1-infected E. coli at various stages of the latent period has been studied. X irradiation of the cells before infection reduces the formation of specific antigen with a two-component inactivation process, some cells being about three times as sensitive as others. X irradiation destroys the ability of free phage to combine with antiserum, but with a very low sensitivity. The ability to produce infectious centers is affected by x rays with a higher sensitivity than for antigen synthesis. The capacity to produce infectious centers is affected by x rays applied before infection, again with a two-component process. At later stages in the multiplication process there appears a less sensitive component which can be identified with mature phage. Irradiation with deuterons and alpha particles of various LET follows the same pattern. The data are consistent with the existence of a single sensitive synthetic site which could be determined by a DNA chain of length 0.97 mu for protein synthesis and 2.5 mu for the formation of infectious centers." @default.
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- W2000647623 date "1958-05-01" @default.
- W2000647623 modified "2023-09-25" @default.
- W2000647623 title "The Effect of Ionizing Radiation on the Synthesis of T1 Phage Protein" @default.
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- W2000647623 doi "https://doi.org/10.2307/3570522" @default.
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