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- W2000650136 abstract "Hydroxyurea (HU) is an antineoplastic drug used in the treatment of chronic myeloproliferative neoplasms (MPNs). HU is associated with cutaneous adverse effects, whereas severe complications such as leg ulcers and non-melanoma skin cancers (NMSCs) are rare and only observed after long-term treatment. We herein report a patient with essential thrombocythemia (ET) treated chronically with HU, and who developed refractory bilateral leg ulcers complicated by squamous cell carcinoma (SCC) over both heels. The patient was successfully managed by multiple debridement stages and skin grafting surgeries." @default.
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- W2000650136 date "2014-12-01" @default.
- W2000650136 modified "2023-09-26" @default.
- W2000650136 title "Successful treatment of hydroxyurea-associated chronic leg ulcers associated with squamous cell carcinoma" @default.
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- W2000650136 doi "https://doi.org/10.1016/j.hemonc.2014.09.008" @default.
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