Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000655848> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2000655848 endingPage "327" @default.
- W2000655848 startingPage "307" @default.
- W2000655848 abstract "Addition of a suspension of a surface membrane enriched fraction prepared from confluent 3T3 cells to sparse 3T3 cells in culture results in a concentration dependent and saturable decrease in the rate of DNA synthesis. The inhibition of cell growth by membranes resembles the inhibition of cell growth observed at confluent cell densities by a number of criteria: (1) In both cases the cells are arrested in the G1 protion of the cell cycle; (2) the inhibition by membranes or by high local cell density can to a large extent be compensated for by raising the serum concentration or by addition of fibroblast growth factor plus dexamethasone. Membranes prepared from sparse cultures inhibit less well than membranes from confluent cultures in a manner which suggests that binding of membranes to cells is not by itself sufficient to cause inhibition of cell growth. The inhibitory activity has a subcellular distribution similar to phosphodiesterase (a plasma membrane marker) and appears to reside in one or more intrinsic membrane components. Maximally, membranes can arrest about 40% of the cell population in each cell cycle. Plasma membranes obtained from sparse 3T3 cells are less inhibitory than membranes obtained from confluent cells. This suggests either that the inhibitory component(s) in the plasma membrane responsible for growth inhibition may be in part induced by high cell density, or that this component(s) may be lost from these membranes during purification." @default.
- W2000655848 created "2016-06-24" @default.
- W2000655848 creator A5064563742 @default.
- W2000655848 creator A5066263005 @default.
- W2000655848 creator A5074337707 @default.
- W2000655848 date "1979-01-01" @default.
- W2000655848 modified "2023-10-16" @default.
- W2000655848 title "Regulation of the cell cycle of 3T3 cells in culture by a surface membrane-enriched cell fraction" @default.
- W2000655848 cites W1964504520 @default.
- W2000655848 cites W1964784148 @default.
- W2000655848 cites W1971182101 @default.
- W2000655848 cites W1976686741 @default.
- W2000655848 cites W1979917750 @default.
- W2000655848 cites W1993344738 @default.
- W2000655848 cites W2000054385 @default.
- W2000655848 cites W2003210027 @default.
- W2000655848 cites W2009668940 @default.
- W2000655848 cites W2026766448 @default.
- W2000655848 cites W2034604567 @default.
- W2000655848 cites W2037002173 @default.
- W2000655848 cites W2041607483 @default.
- W2000655848 cites W2052588630 @default.
- W2000655848 cites W2052970532 @default.
- W2000655848 cites W2062993711 @default.
- W2000655848 cites W2064670731 @default.
- W2000655848 cites W2078429643 @default.
- W2000655848 cites W2094891357 @default.
- W2000655848 cites W2126818181 @default.
- W2000655848 cites W2161829332 @default.
- W2000655848 doi "https://doi.org/10.1002/jss.400100304" @default.
- W2000655848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/491660" @default.
- W2000655848 hasPublicationYear "1979" @default.
- W2000655848 type Work @default.
- W2000655848 sameAs 2000655848 @default.
- W2000655848 citedByCount "23" @default.
- W2000655848 crossrefType "journal-article" @default.
- W2000655848 hasAuthorship W2000655848A5064563742 @default.
- W2000655848 hasAuthorship W2000655848A5066263005 @default.
- W2000655848 hasAuthorship W2000655848A5074337707 @default.
- W2000655848 hasConcept C144024400 @default.
- W2000655848 hasConcept C1491633281 @default.
- W2000655848 hasConcept C149923435 @default.
- W2000655848 hasConcept C2776746612 @default.
- W2000655848 hasConcept C2778106830 @default.
- W2000655848 hasConcept C2908647359 @default.
- W2000655848 hasConcept C29537977 @default.
- W2000655848 hasConcept C41625074 @default.
- W2000655848 hasConcept C54009773 @default.
- W2000655848 hasConcept C54355233 @default.
- W2000655848 hasConcept C55493867 @default.
- W2000655848 hasConcept C62112901 @default.
- W2000655848 hasConcept C64979461 @default.
- W2000655848 hasConcept C81885089 @default.
- W2000655848 hasConcept C86803240 @default.
- W2000655848 hasConcept C95444343 @default.
- W2000655848 hasConceptScore W2000655848C144024400 @default.
- W2000655848 hasConceptScore W2000655848C1491633281 @default.
- W2000655848 hasConceptScore W2000655848C149923435 @default.
- W2000655848 hasConceptScore W2000655848C2776746612 @default.
- W2000655848 hasConceptScore W2000655848C2778106830 @default.
- W2000655848 hasConceptScore W2000655848C2908647359 @default.
- W2000655848 hasConceptScore W2000655848C29537977 @default.
- W2000655848 hasConceptScore W2000655848C41625074 @default.
- W2000655848 hasConceptScore W2000655848C54009773 @default.
- W2000655848 hasConceptScore W2000655848C54355233 @default.
- W2000655848 hasConceptScore W2000655848C55493867 @default.
- W2000655848 hasConceptScore W2000655848C62112901 @default.
- W2000655848 hasConceptScore W2000655848C64979461 @default.
- W2000655848 hasConceptScore W2000655848C81885089 @default.
- W2000655848 hasConceptScore W2000655848C86803240 @default.
- W2000655848 hasConceptScore W2000655848C95444343 @default.
- W2000655848 hasIssue "3" @default.
- W2000655848 hasLocation W20006558481 @default.
- W2000655848 hasLocation W20006558482 @default.
- W2000655848 hasOpenAccess W2000655848 @default.
- W2000655848 hasPrimaryLocation W20006558481 @default.
- W2000655848 hasRelatedWork W2000185587 @default.
- W2000655848 hasRelatedWork W2014534222 @default.
- W2000655848 hasRelatedWork W2066519212 @default.
- W2000655848 hasRelatedWork W2072481810 @default.
- W2000655848 hasRelatedWork W2083693850 @default.
- W2000655848 hasRelatedWork W2111353121 @default.
- W2000655848 hasRelatedWork W2373495330 @default.
- W2000655848 hasRelatedWork W2374592133 @default.
- W2000655848 hasRelatedWork W2387175565 @default.
- W2000655848 hasRelatedWork W4280493527 @default.
- W2000655848 hasVolume "10" @default.
- W2000655848 isParatext "false" @default.
- W2000655848 isRetracted "false" @default.
- W2000655848 magId "2000655848" @default.
- W2000655848 workType "article" @default.