Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000655876> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2000655876 endingPage "826" @default.
- W2000655876 startingPage "818" @default.
- W2000655876 abstract "Evaluation of the efficacy of allergen-specific immunotherapy (IT) with pollen extracts is complicated by annual variation in pollen intensity. Our study aimed to evaluate the efficacy of birch and grass IT, taking into consideration these variations.After 1 year of observation, 52 patients with rhinoconjunctivitis and allergy to birch as well as grass pollen were allocated to double-blinded clustered IT with aluminum-adsorbed extract produced from either birch (Betula verrucosa) pollen or grass (PIleum pratense) pollen. After 1 year of treatment, the patients continued IT with their original extract and also received the other extract. During the three consecutive pollen seasons, the rhinoconjunctivitis symptom score and the use of antihistamines, eye-drops, and oral prednisolone were recorded. Longitudinal data analysis was used to investigate the relation between different pollen counts and the magnitude of clinical efficacy.An effect of IT was found on symptom score, antihistamine intake, and eye-drop use for both birch and grass (P values <0.05). The mean reduction in symptom score/medication by IT ranged from 24% to 95%, depending on mean seasonal pollen counts. A minimum mean seasonal grass-pollen count of 20-30 pollen grains m3 was required for the efficacy of grass IT to emerge.A model was developed for evaluation of efficacy in longitudinal IT studies, taking the differences in annual pollen counts into consideration. The model showed a significant beneficial role of pollen IT in rhinoconjunctivitis patients allergic to birch and grass pollen." @default.
- W2000655876 created "2016-06-24" @default.
- W2000655876 creator A5010039943 @default.
- W2000655876 creator A5023071631 @default.
- W2000655876 creator A5057978547 @default.
- W2000655876 creator A5079964062 @default.
- W2000655876 date "2000-09-01" @default.
- W2000655876 modified "2023-10-16" @default.
- W2000655876 title "Allergen-specific immunotherapy in birch- and grass-pollen-allergic rhinitis. I. Efficacy estimated by a model reducing the biasof annual differences in pollen counts" @default.
- W2000655876 cites W1500543702 @default.
- W2000655876 cites W1544152039 @default.
- W2000655876 cites W1945242940 @default.
- W2000655876 cites W1970877567 @default.
- W2000655876 cites W1977121058 @default.
- W2000655876 cites W1984062235 @default.
- W2000655876 cites W1988717049 @default.
- W2000655876 cites W2042506161 @default.
- W2000655876 cites W2057401926 @default.
- W2000655876 cites W2071845238 @default.
- W2000655876 cites W2093740248 @default.
- W2000655876 cites W2105259124 @default.
- W2000655876 cites W2161091193 @default.
- W2000655876 cites W2467022164 @default.
- W2000655876 cites W2498823163 @default.
- W2000655876 cites W3026766594 @default.
- W2000655876 doi "https://doi.org/10.1034/j.1398-9995.2000.00367.x" @default.
- W2000655876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11003445" @default.
- W2000655876 hasPublicationYear "2000" @default.
- W2000655876 type Work @default.
- W2000655876 sameAs 2000655876 @default.
- W2000655876 citedByCount "44" @default.
- W2000655876 countsByYear W20006558762012 @default.
- W2000655876 countsByYear W20006558762013 @default.
- W2000655876 countsByYear W20006558762016 @default.
- W2000655876 countsByYear W20006558762018 @default.
- W2000655876 countsByYear W20006558762019 @default.
- W2000655876 crossrefType "journal-article" @default.
- W2000655876 hasAuthorship W2000655876A5010039943 @default.
- W2000655876 hasAuthorship W2000655876A5023071631 @default.
- W2000655876 hasAuthorship W2000655876A5057978547 @default.
- W2000655876 hasAuthorship W2000655876A5079964062 @default.
- W2000655876 hasConcept C203014093 @default.
- W2000655876 hasConcept C207480886 @default.
- W2000655876 hasConcept C2776880894 @default.
- W2000655876 hasConcept C2776949755 @default.
- W2000655876 hasConcept C2777037608 @default.
- W2000655876 hasConcept C2780510475 @default.
- W2000655876 hasConcept C2780618852 @default.
- W2000655876 hasConcept C59822182 @default.
- W2000655876 hasConcept C71924100 @default.
- W2000655876 hasConcept C86803240 @default.
- W2000655876 hasConceptScore W2000655876C203014093 @default.
- W2000655876 hasConceptScore W2000655876C207480886 @default.
- W2000655876 hasConceptScore W2000655876C2776880894 @default.
- W2000655876 hasConceptScore W2000655876C2776949755 @default.
- W2000655876 hasConceptScore W2000655876C2777037608 @default.
- W2000655876 hasConceptScore W2000655876C2780510475 @default.
- W2000655876 hasConceptScore W2000655876C2780618852 @default.
- W2000655876 hasConceptScore W2000655876C59822182 @default.
- W2000655876 hasConceptScore W2000655876C71924100 @default.
- W2000655876 hasConceptScore W2000655876C86803240 @default.
- W2000655876 hasIssue "9" @default.
- W2000655876 hasLocation W20006558761 @default.
- W2000655876 hasLocation W20006558762 @default.
- W2000655876 hasOpenAccess W2000655876 @default.
- W2000655876 hasPrimaryLocation W20006558761 @default.
- W2000655876 hasRelatedWork W1538507717 @default.
- W2000655876 hasRelatedWork W1992540251 @default.
- W2000655876 hasRelatedWork W2000655876 @default.
- W2000655876 hasRelatedWork W2041899354 @default.
- W2000655876 hasRelatedWork W2054114633 @default.
- W2000655876 hasRelatedWork W2073352341 @default.
- W2000655876 hasRelatedWork W2091261329 @default.
- W2000655876 hasRelatedWork W2111715937 @default.
- W2000655876 hasRelatedWork W2128436686 @default.
- W2000655876 hasRelatedWork W2140433953 @default.
- W2000655876 hasVolume "55" @default.
- W2000655876 isParatext "false" @default.
- W2000655876 isRetracted "false" @default.
- W2000655876 magId "2000655876" @default.
- W2000655876 workType "article" @default.