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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000658199> ?p ?o ?g. }

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• W2000658199 abstract "RunX2 has been identified to crucially regulate the osteolysis in giant cell tumor of bone. MiR-30a is an intronic miRNA identified as tumor suppressor, but little is known about its role in giant tumor cell of bone. In our research, we reported miR-30a was down-regulated in GCT whereas RunX2 was highly expressed. Further research proved that miR-30a can regulate the expression of RunX2 by binding to its 3′-UTR, which influence the osteoclast differentiation and osteolysis formation. Thus, these results suggest that miR-30a could directly target RunX2 and participate in osteolysis in GCT." @default.
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• W2000658199 date "2014-10-01" @default.
• W2000658199 modified "2023-10-16" @default.
• W2000658199 title "MiR-30a inhibits osteolysis by targeting RunX2 in giant cell tumor of bone" @default.
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• W2000658199 doi "https://doi.org/10.1016/j.bbrc.2014.09.076" @default.
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