FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000662641> ?p ?o ?g. }

• W2000662641 endingPage "1344" @default.
• W2000662641 startingPage "1338" @default.
• W2000662641 abstract "Little is known about the immunotoxic effects of sublethal mercury (Hg) exposure in bivalves, and whether or not stimulation of the immune system exacerbates Hg toxicity. The mussel, Mytilus edulis, was exposed to a total inorganic Hg concentration of 50 microgl(-1) as HgCl2 for up to 11 days compared to no added Hg controls. Then the immune functions of haemocytes, haematology, biochemistry and organ histology were assessed. Selected experiments were then repeated in mussels injected with lipopolysaccharide (LPS) to stimulate the immune system prior to Hg exposure. Hg exposure alone caused Hg accumulation mainly in gills and digestive gland, and to a lesser extent in the adductor muscle and haemolymph. This general pattern of Hg accumulation also occurred during the Hg plus LPS experiments. Hg exposure alone caused a transient increase of phagocytosis, but no Hg-dependent effects on neutral red retention or the cytotoxicity of haemocytes. Changes in haemolymph Na+, K+ and glucose levels were negligible during Hg exposure alone compared to controls. However, histological examination showed tissues injuries consistent with inflammation in the gills, digestive gland and adductor muscle during Hg exposure alone. LPS injection had a significant effect (Kruskal Wallis, P=0.02) on circulating haemocytes numbers at the end of the experiment compared to saline injected controls and the Hg+LPS treatment (mean+/-S.E.M., n=6, cells ml(-1)x10(6)); control, 2.1+/-0.08; LPS treated, 3.18+/-0.36, and LPS+Hg, 2.1+/-0.2. The Hg+LPS treatment also caused a transient decline in superoxide dismutase activity in haemocytes (85% decline, Kruskal Wallis, P=0.006) compared to controls. Target tissue inflammation and injury was greatly increased by the effect of Hg exposure with an LPS injection compared to either treatment alone. We conclude that Hg can cause inflammation in mussels in vivo, and that stimulation with LPS can greatly increase Hg-dependent immunotoxicity." @default.
• W2000662641 created "2016-06-24" @default.
• W2000662641 creator A5041196638 @default.
• W2000662641 creator A5048146972 @default.
• W2000662641 creator A5088403838 @default.
• W2000662641 date "2010-09-01" @default.
• W2000662641 modified "2023-09-24" @default.
• W2000662641 title "Tissue injury and cellular immune responses to mercuric chloride exposure in the common mussel Mytilus edulis: Modulation by lipopolysaccharide" @default.
• W2000662641 cites W1580414888 @default.
• W2000662641 cites W1940436875 @default.
• W2000662641 cites W1959170413 @default.
• W2000662641 cites W1964123007 @default.
• W2000662641 cites W1964343287 @default.
• W2000662641 cites W1965754304 @default.
• W2000662641 cites W1973731340 @default.
• W2000662641 cites W1973751291 @default.
• W2000662641 cites W19744801 @default.
• W2000662641 cites W1978611085 @default.
• W2000662641 cites W1984346545 @default.
• W2000662641 cites W1991578247 @default.
• W2000662641 cites W1995631269 @default.
• W2000662641 cites W2001787367 @default.
• W2000662641 cites W2006728884 @default.
• W2000662641 cites W2011611780 @default.
• W2000662641 cites W2012722985 @default.
• W2000662641 cites W2013344058 @default.
• W2000662641 cites W2015238625 @default.
• W2000662641 cites W2023286233 @default.
• W2000662641 cites W2026170500 @default.
• W2000662641 cites W2028480207 @default.
• W2000662641 cites W2035192516 @default.
• W2000662641 cites W2042272309 @default.
• W2000662641 cites W2047715694 @default.
• W2000662641 cites W2051055564 @default.
• W2000662641 cites W2054719389 @default.
• W2000662641 cites W20646326 @default.
• W2000662641 cites W2081357400 @default.
• W2000662641 cites W2093910437 @default.
• W2000662641 cites W2113828544 @default.
• W2000662641 cites W2149711604 @default.
• W2000662641 cites W2158892056 @default.
• W2000662641 cites W2167471997 @default.
• W2000662641 cites W4246887305 @default.
• W2000662641 doi "https://doi.org/10.1016/j.ecoenv.2010.01.014" @default.
• W2000662641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20598371" @default.
• W2000662641 hasPublicationYear "2010" @default.
• W2000662641 type Work @default.
• W2000662641 sameAs 2000662641 @default.
• W2000662641 citedByCount "37" @default.
• W2000662641 countsByYear W20006626412012 @default.
• W2000662641 countsByYear W20006626412013 @default.
• W2000662641 countsByYear W20006626412014 @default.
• W2000662641 countsByYear W20006626412015 @default.
• W2000662641 countsByYear W20006626412016 @default.
• W2000662641 countsByYear W20006626412017 @default.
• W2000662641 countsByYear W20006626412018 @default.
• W2000662641 countsByYear W20006626412019 @default.
• W2000662641 countsByYear W20006626412020 @default.
• W2000662641 countsByYear W20006626412021 @default.
• W2000662641 countsByYear W20006626412022 @default.
• W2000662641 countsByYear W20006626412023 @default.
• W2000662641 crossrefType "journal-article" @default.
• W2000662641 hasAuthorship W2000662641A5041196638 @default.
• W2000662641 hasAuthorship W2000662641A5048146972 @default.
• W2000662641 hasAuthorship W2000662641A5088403838 @default.
• W2000662641 hasConcept C100068826 @default.
• W2000662641 hasConcept C105702510 @default.
• W2000662641 hasConcept C126322002 @default.
• W2000662641 hasConcept C134018914 @default.
• W2000662641 hasConcept C161153951 @default.
• W2000662641 hasConcept C185592680 @default.
• W2000662641 hasConcept C18903297 @default.
• W2000662641 hasConcept C203014093 @default.
• W2000662641 hasConcept C2778754761 @default.
• W2000662641 hasConcept C2779909984 @default.
• W2000662641 hasConcept C2779987062 @default.
• W2000662641 hasConcept C2781237507 @default.
• W2000662641 hasConcept C2909208804 @default.
• W2000662641 hasConcept C29730261 @default.
• W2000662641 hasConcept C505870484 @default.
• W2000662641 hasConcept C55493867 @default.
• W2000662641 hasConcept C71924100 @default.
• W2000662641 hasConcept C86803240 @default.
• W2000662641 hasConcept C8891405 @default.
• W2000662641 hasConceptScore W2000662641C100068826 @default.
• W2000662641 hasConceptScore W2000662641C105702510 @default.
• W2000662641 hasConceptScore W2000662641C126322002 @default.
• W2000662641 hasConceptScore W2000662641C134018914 @default.
• W2000662641 hasConceptScore W2000662641C161153951 @default.
• W2000662641 hasConceptScore W2000662641C185592680 @default.
• W2000662641 hasConceptScore W2000662641C18903297 @default.
• W2000662641 hasConceptScore W2000662641C203014093 @default.
• W2000662641 hasConceptScore W2000662641C2778754761 @default.
• W2000662641 hasConceptScore W2000662641C2779909984 @default.
• W2000662641 hasConceptScore W2000662641C2779987062 @default.
• W2000662641 hasConceptScore W2000662641C2781237507 @default.
• W2000662641 hasConceptScore W2000662641C2909208804 @default.
• W2000662641 hasConceptScore W2000662641C29730261 @default.

• next