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- W2000663352 abstract "Une patiente de 29 ans développe une hypertension artérielle sévère dès le début d'une deuxième grossesse. Le bilan pratiqué à 16 semaines d'aménorrhée montre une hypokaliémie en relation avec un hyper-réninisme important, le taux de rénine active étant à 25 fois la normale, le taux de prorénine représentant 94 % de la rénine totale. L'étude radiologique comprenant échographie et imagerie en résonance magnétique fera la preuve d'une néoformation homogène, avasculaire, du rein droit. Son ablation confirmera la tumeur à rénine et entraînera la guérison de l'hypertension permettant à la grossesse d'évoluer normalement. Ce nouveau cas porte à 75 le nombre de réninomes retrouvés dans la littérature, permettant de refaire le point sur les démarches diagnostiques et thérapeutiques, modifiées au cours de la gestation par la contre-indication aux rayons X et aux inhibiteurs de l'axe rénine–angiotensine–aldostérone. A 29 year-old female patient developed severe arterial hypertension in the beginning of her second pregnancy. Investigations performed at 16 weeks of amenorrhea showed hypokaliemia in relation to severe hyperreninism: plasma active renin was 25 fold normal value, 94% as prorenin (prorenin representing 94% of total renin). Radiological investigations including ultrasonography and MRI disclosed an homogenous and avascular tumor in the right kidney. Its ablation confirmed renin tumor, and allowed recovery from HTA and continuation of pregnancy. This is the 75th reported case in the literature, enabling to make a new statement about diagnostic and therapeutic procedures, which are modified during pregnancy by contra-indication to X-rays and renin-angiotensin-aldosteron axis inhibitors." @default.
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- W2000663352 date "2005-03-01" @default.
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- W2000663352 title "Tumeur à rénine. À propos d'un nouveau cas diagnostiqué au cours d'une grossesse" @default.
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- W2000663352 doi "https://doi.org/10.1016/j.nephro.2005.01.008" @default.
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