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- W2000664344 abstract "Induction of sex-linked recessive lethal mutations, heritable translocations and genetic crossing-over were studied in Drosophila melanogaster males treated as adults and as embryos with different concentrations of gaseous DBCP. Adults exposed to 30 ppm/hr of the compound did not produce a significant number of sex-linked recessive lethal mutations in treated spermatozoa, spermatids, or spermato-cytes. However, at an exposure of 17.7 ppm/hr, a weak mutagenic effect was observed in embryonic spermatogonia. No translocation was scored in 4032 tested chromosomes from adults treated with 150 ppm/hr. However, a significant number of spermatocytial crossovers were induced after an exposure of 120 ppm/hr." @default.
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- W2000664344 date "1982-01-01" @default.
- W2000664344 modified "2023-09-26" @default.
- W2000664344 title "Genetic effects of 1,2-dibromo-3-chloropropane (DBCP) in drosophila" @default.
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- W2000664344 doi "https://doi.org/10.1002/em.2860040607" @default.
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