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- W2000666772 abstract "Temperature-sensitive growth mutants of mouse mammary carcinoma cell line FM3A were isolated by selecting survivors of thymidylate starvation for a limited time at the restrictive temperature (39.5°C). Nineteen lines of independent isolates were established and all were found to be deficient in DNA synthesis. Cell-cell hybridization with authentic mutant of FM3A demonstrated that the mutants fell into three complementation groups, ehich were deficient in DNA polymerase α or uniquitin-activating enzyme E1 or both." @default.
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- W2000666772 date "1993-09-01" @default.
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- W2000666772 title "Conditional resistance to thymineless death predominantly selects DNA synthesis-deficient mutants of mammalian cells" @default.
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- W2000666772 doi "https://doi.org/10.1016/0027-5107(93)90133-z" @default.
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