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- W2000666923 abstract "6-methylpurine 2′-deoxyriboside killed mouse macrophages infected with amastigotes of Leishmania donovani and Leishmania mexicana, but did not affect the growth of non-parasitized cells. Leishmania extracts cleaved the non-toxic 6-methylpurine 2′-deoxyriboside to 6-methylpurine, a potent adenine antimetabolite for mammalian cells. By eliminating macrophages latently infected with Leishmania donovani amastigotes, 6-methylpurine 2′-deoxyriboside could augment the effects of leishmanicidal agents in vivo." @default.
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- W2000666923 date "1981-10-01" @default.
- W2000666923 modified "2023-10-16" @default.
- W2000666923 title "Selective killing of Leishmania infected mouse macrophages by 6-methylpurine 2′-deoxyriboside" @default.
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- W2000666923 doi "https://doi.org/10.1016/0024-3205(81)90062-x" @default.
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