Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000668855> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2000668855 abstract "Angiogenesis is the growth process of blood vessels from existing vessels. During angiogenesis, endothelial cells (ECs), which line the vessel, specialize into tip and stalk cells. Tip cells respond to angiogenic signals, burrow into the extracellular matrix (ECM) and form conduits. Stalk cells follow the tip cells along the conduits, and form solid sprouts or lumen vessels. Interactions between stalk cells and tip cells are important for creating functional vessels. The goal of this work is to predict stalk cells migration trajectories from known tip cell trajectories. Four factors influence the position and velocity of cell migration in ECM: cell-cell interaction, drag force, chemotactic signal and cell-ECM interaction. As chemotactic signal and cell-ECM interactions have little effect on stalk cell movement, the proposed model includes the influence of cell-cell interactions and drag force only. The unknown parameters in the model are inferred by Maximum Likelihood Estimation (MLE) from experimental time-lapse cell migration data. Numerical results suggest that the proposed model can accurately predict stalk cell trajectories. The proposed model may be useful for the study of angiogenesis, a critical process for cancer tumor growth." @default.
- W2000668855 created "2016-06-24" @default.
- W2000668855 creator A5011250352 @default.
- W2000668855 creator A5052924669 @default.
- W2000668855 creator A5069522797 @default.
- W2000668855 creator A5082613025 @default.
- W2000668855 date "2013-07-01" @default.
- W2000668855 modified "2023-09-23" @default.
- W2000668855 title "2D data-driven stalk cell prediction model based on tip-stalk cell interaction in angiogenesis" @default.
- W2000668855 cites W1968680922 @default.
- W2000668855 cites W1981479595 @default.
- W2000668855 cites W2014455063 @default.
- W2000668855 cites W2029389605 @default.
- W2000668855 cites W2034957927 @default.
- W2000668855 cites W2048195900 @default.
- W2000668855 cites W2071164466 @default.
- W2000668855 cites W2106447658 @default.
- W2000668855 cites W2127225632 @default.
- W2000668855 cites W2134066908 @default.
- W2000668855 cites W2146956723 @default.
- W2000668855 cites W2157930949 @default.
- W2000668855 doi "https://doi.org/10.1109/embc.2013.6610556" @default.
- W2000668855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24110743" @default.
- W2000668855 hasPublicationYear "2013" @default.
- W2000668855 type Work @default.
- W2000668855 sameAs 2000668855 @default.
- W2000668855 citedByCount "0" @default.
- W2000668855 crossrefType "proceedings-article" @default.
- W2000668855 hasAuthorship W2000668855A5011250352 @default.
- W2000668855 hasAuthorship W2000668855A5052924669 @default.
- W2000668855 hasAuthorship W2000668855A5069522797 @default.
- W2000668855 hasAuthorship W2000668855A5082613025 @default.
- W2000668855 hasBestOaLocation W20006688552 @default.
- W2000668855 hasConcept C121332964 @default.
- W2000668855 hasConcept C144027150 @default.
- W2000668855 hasConcept C1491633281 @default.
- W2000668855 hasConcept C170493617 @default.
- W2000668855 hasConcept C189165786 @default.
- W2000668855 hasConcept C2779560860 @default.
- W2000668855 hasConcept C2780394083 @default.
- W2000668855 hasConcept C502942594 @default.
- W2000668855 hasConcept C54166955 @default.
- W2000668855 hasConcept C55493867 @default.
- W2000668855 hasConcept C57879066 @default.
- W2000668855 hasConcept C72921944 @default.
- W2000668855 hasConcept C86803240 @default.
- W2000668855 hasConcept C95444343 @default.
- W2000668855 hasConceptScore W2000668855C121332964 @default.
- W2000668855 hasConceptScore W2000668855C144027150 @default.
- W2000668855 hasConceptScore W2000668855C1491633281 @default.
- W2000668855 hasConceptScore W2000668855C170493617 @default.
- W2000668855 hasConceptScore W2000668855C189165786 @default.
- W2000668855 hasConceptScore W2000668855C2779560860 @default.
- W2000668855 hasConceptScore W2000668855C2780394083 @default.
- W2000668855 hasConceptScore W2000668855C502942594 @default.
- W2000668855 hasConceptScore W2000668855C54166955 @default.
- W2000668855 hasConceptScore W2000668855C55493867 @default.
- W2000668855 hasConceptScore W2000668855C57879066 @default.
- W2000668855 hasConceptScore W2000668855C72921944 @default.
- W2000668855 hasConceptScore W2000668855C86803240 @default.
- W2000668855 hasConceptScore W2000668855C95444343 @default.
- W2000668855 hasLocation W20006688551 @default.
- W2000668855 hasLocation W20006688552 @default.
- W2000668855 hasLocation W20006688553 @default.
- W2000668855 hasOpenAccess W2000668855 @default.
- W2000668855 hasPrimaryLocation W20006688551 @default.
- W2000668855 hasRelatedWork W2052766257 @default.
- W2000668855 hasRelatedWork W2089099584 @default.
- W2000668855 hasRelatedWork W2091139028 @default.
- W2000668855 hasRelatedWork W2104121252 @default.
- W2000668855 hasRelatedWork W2151128289 @default.
- W2000668855 hasRelatedWork W2205357876 @default.
- W2000668855 hasRelatedWork W2993990633 @default.
- W2000668855 hasRelatedWork W4211152410 @default.
- W2000668855 hasRelatedWork W2346703409 @default.
- W2000668855 hasRelatedWork W3151918802 @default.
- W2000668855 isParatext "false" @default.
- W2000668855 isRetracted "false" @default.
- W2000668855 magId "2000668855" @default.
- W2000668855 workType "article" @default.