FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000669626> ?p ?o ?g. }

• W2000669626 endingPage "1152" @default.
• W2000669626 startingPage "1147" @default.
• W2000669626 abstract "Adults with cystic fibrosis (CF) possess multiple potential risk factors for chronic kidney disease, including CF-related diabetes (CFRD) and lifetime nephrotoxic drug exposure.To determine whether cumulative intravenous (IV) aminoglycoside exposure and CFRD increase the risk of chronic kidney disease in adults with CF.This was a cohort study using adults (≥ 18 yr) in the CF Foundation registry from 2001-2008. Chronic kidney disease (stage 3 or greater) was defined by an estimated glomerular filtration rate of less than 60 ml/min/1.73 m(2). Time-dependent multivariable Cox proportional hazards models were used to determine whether cumulative number of acute pulmonary exacerbations (surrogate for IV aminoglycoside exposure) and CFRD requiring insulin increase the risk of chronic kidney disease, adjusting for confounders.The study cohort included 11,912 adults with a median follow-up of 4 years. During the study period, 204 subjects had chronic kidney disease, with an annual disease prevalence of 2.3%. Disease prevalence doubled with every 10-year increase in age. CFRD requiring insulin therapy substantially increased the risk of chronic kidney disease (1-4 yr of CFRD requiring insulin vs. no CFRD, hazard ratio [HR] = 2.40, 95% confidence interval [CI] 1.74-3.32; ≥ 5 yr, HR = 4.56, 95% CI 2.84-7.31). Pulmonary exacerbations did not significantly increase the risk of chronic kidney disease (one to five exacerbations vs. none, HR = 0.79, 95% CI 0.56-1.11; six to nine exacerbations, HR = 0.92, 95% CI 0.58-1.46; ≥ 10 exacerbations, HR = 1.16, 95% CI 0.75-1.81).CF-related diabetes is a significant risk factor for chronic kidney disease in adults with CF, but additional studies examining IV aminoglycoside exposure directly are required." @default.
• W2000669626 created "2016-06-24" @default.
• W2000669626 creator A5008923724 @default.
• W2000669626 creator A5032042043 @default.
• W2000669626 creator A5062599923 @default.
• W2000669626 creator A5081128925 @default.
• W2000669626 creator A5082827731 @default.
• W2000669626 date "2011-11-15" @default.
• W2000669626 modified "2023-10-03" @default.
• W2000669626 title "Risk Factors for Chronic Kidney Disease in Adults with Cystic Fibrosis" @default.
• W2000669626 cites W1487297692 @default.
• W2000669626 cites W1550111394 @default.
• W2000669626 cites W1963953120 @default.
• W2000669626 cites W1973109789 @default.
• W2000669626 cites W1985069389 @default.
• W2000669626 cites W1985242328 @default.
• W2000669626 cites W1990987230 @default.
• W2000669626 cites W1992283514 @default.
• W2000669626 cites W2006605675 @default.
• W2000669626 cites W2011727302 @default.
• W2000669626 cites W2018300612 @default.
• W2000669626 cites W2019159967 @default.
• W2000669626 cites W2019256505 @default.
• W2000669626 cites W2034055729 @default.
• W2000669626 cites W2034996827 @default.
• W2000669626 cites W2038485127 @default.
• W2000669626 cites W2045516356 @default.
• W2000669626 cites W2061909665 @default.
• W2000669626 cites W2070404021 @default.
• W2000669626 cites W2105915947 @default.
• W2000669626 cites W2108814590 @default.
• W2000669626 cites W2109801094 @default.
• W2000669626 cites W2130878552 @default.
• W2000669626 cites W2132707658 @default.
• W2000669626 cites W2139226586 @default.
• W2000669626 cites W2140801627 @default.
• W2000669626 cites W2157745572 @default.
• W2000669626 cites W2293035635 @default.
• W2000669626 cites W2317332612 @default.
• W2000669626 cites W2326999967 @default.
• W2000669626 doi "https://doi.org/10.1164/rccm.201105-0932oc" @default.
• W2000669626 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3262023" @default.
• W2000669626 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21799076" @default.
• W2000669626 hasPublicationYear "2011" @default.
• W2000669626 type Work @default.
• W2000669626 sameAs 2000669626 @default.
• W2000669626 citedByCount "68" @default.
• W2000669626 countsByYear W20006696262012 @default.
• W2000669626 countsByYear W20006696262013 @default.
• W2000669626 countsByYear W20006696262014 @default.
• W2000669626 countsByYear W20006696262015 @default.
• W2000669626 countsByYear W20006696262016 @default.
• W2000669626 countsByYear W20006696262017 @default.
• W2000669626 countsByYear W20006696262018 @default.
• W2000669626 countsByYear W20006696262019 @default.
• W2000669626 countsByYear W20006696262020 @default.
• W2000669626 countsByYear W20006696262021 @default.
• W2000669626 countsByYear W20006696262022 @default.
• W2000669626 countsByYear W20006696262023 @default.
• W2000669626 crossrefType "journal-article" @default.
• W2000669626 hasAuthorship W2000669626A5008923724 @default.
• W2000669626 hasAuthorship W2000669626A5032042043 @default.
• W2000669626 hasAuthorship W2000669626A5062599923 @default.
• W2000669626 hasAuthorship W2000669626A5081128925 @default.
• W2000669626 hasAuthorship W2000669626A5082827731 @default.
• W2000669626 hasBestOaLocation W20006696262 @default.
• W2000669626 hasConcept C126322002 @default.
• W2000669626 hasConcept C134018914 @default.
• W2000669626 hasConcept C159641895 @default.
• W2000669626 hasConcept C201903717 @default.
• W2000669626 hasConcept C207103383 @default.
• W2000669626 hasConcept C2776938444 @default.
• W2000669626 hasConcept C2778653478 @default.
• W2000669626 hasConcept C44249647 @default.
• W2000669626 hasConcept C50382708 @default.
• W2000669626 hasConcept C50440223 @default.
• W2000669626 hasConcept C555293320 @default.
• W2000669626 hasConcept C71924100 @default.
• W2000669626 hasConcept C72563966 @default.
• W2000669626 hasConceptScore W2000669626C126322002 @default.
• W2000669626 hasConceptScore W2000669626C134018914 @default.
• W2000669626 hasConceptScore W2000669626C159641895 @default.
• W2000669626 hasConceptScore W2000669626C201903717 @default.
• W2000669626 hasConceptScore W2000669626C207103383 @default.
• W2000669626 hasConceptScore W2000669626C2776938444 @default.
• W2000669626 hasConceptScore W2000669626C2778653478 @default.
• W2000669626 hasConceptScore W2000669626C44249647 @default.
• W2000669626 hasConceptScore W2000669626C50382708 @default.
• W2000669626 hasConceptScore W2000669626C50440223 @default.
• W2000669626 hasConceptScore W2000669626C555293320 @default.
• W2000669626 hasConceptScore W2000669626C71924100 @default.
• W2000669626 hasConceptScore W2000669626C72563966 @default.
• W2000669626 hasIssue "10" @default.
• W2000669626 hasLocation W20006696261 @default.
• W2000669626 hasLocation W20006696262 @default.
• W2000669626 hasLocation W20006696263 @default.
• W2000669626 hasLocation W20006696264 @default.
• W2000669626 hasOpenAccess W2000669626 @default.

• next