FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000681096> ?p ?o ?g. }

• W2000681096 abstract "Cataract was induced by a single intraperitoneal injection of N-methyl-N-nitrosourea (MNU) in 15-day-old Sprague-Dawley (Jcl: SD) rats. The threshold dose of MNU required for cataract induction in a 3-4 week time period was 70 mg/kg; 60 mg/kg was ineffective. Males and females were both equally affected. Mature cataract as confirmed histologically by degeneration, swelling, vacuolation, liquefaction of the lens fibers, and formation of Morgagni-like water vacuoles was seen in 80% (8/10), 70% (7/10) and 90% (9/10) of 100, 80 and 70 mg/kg MNU-treated rats, respectively, 4 weeks after dosing (43 days of age). At this time point, lens epithelial apoptosis was only rarely seen, but proliferating cell nuclear antigen (PCNA) labeled atypical nuclei with vacuolated lens fibers and macrophage migration were present within the injured lens. Cataracts were the only lesions induced by MNU and there were no other intra- or extraocular lesions seen. The dosing and timing schedule for the MNU administration in rats used in the present study is effective in rapidly causing cataract to occur." @default.
• W2000681096 created "2016-06-24" @default.
• W2000681096 creator A5018774495 @default.
• W2000681096 creator A5057826873 @default.
• W2000681096 creator A5067758220 @default.
• W2000681096 creator A5091879722 @default.
• W2000681096 date "2002-01-01" @default.
• W2000681096 modified "2023-10-18" @default.
• W2000681096 title "Rapid induction of cataract by a single intraperitoneal administration of N-methyl-N-nitrosourea in 15-day-old Sprague-Dawley (Jcl: SD) rats" @default.
• W2000681096 cites W130435811 @default.
• W2000681096 cites W1873574768 @default.
• W2000681096 cites W1969818728 @default.
• W2000681096 cites W1979412091 @default.
• W2000681096 cites W1982801265 @default.
• W2000681096 cites W2005920245 @default.
• W2000681096 cites W2007769765 @default.
• W2000681096 cites W2011193455 @default.
• W2000681096 cites W2012488868 @default.
• W2000681096 cites W2017140359 @default.
• W2000681096 cites W2026364862 @default.
• W2000681096 cites W2044745020 @default.
• W2000681096 cites W2064379167 @default.
• W2000681096 cites W2080680419 @default.
• W2000681096 cites W2112786757 @default.
• W2000681096 cites W2127008350 @default.
• W2000681096 cites W2153630929 @default.
• W2000681096 cites W2417550881 @default.
• W2000681096 cites W2461427893 @default.
• W2000681096 cites W568406528 @default.
• W2000681096 cites W97340538 @default.
• W2000681096 doi "https://doi.org/10.1078/0940-2993-00253" @default.
• W2000681096 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12484553" @default.
• W2000681096 hasPublicationYear "2002" @default.
• W2000681096 type Work @default.
• W2000681096 sameAs 2000681096 @default.
• W2000681096 citedByCount "10" @default.
• W2000681096 countsByYear W20006810962015 @default.
• W2000681096 countsByYear W20006810962020 @default.
• W2000681096 crossrefType "journal-article" @default.
• W2000681096 hasAuthorship W2000681096A5018774495 @default.
• W2000681096 hasAuthorship W2000681096A5057826873 @default.
• W2000681096 hasAuthorship W2000681096A5067758220 @default.
• W2000681096 hasAuthorship W2000681096A5091879722 @default.
• W2000681096 hasConcept C103796816 @default.
• W2000681096 hasConcept C118487528 @default.
• W2000681096 hasConcept C134018914 @default.
• W2000681096 hasConcept C142724271 @default.
• W2000681096 hasConcept C16685009 @default.
• W2000681096 hasConcept C185592680 @default.
• W2000681096 hasConcept C190283241 @default.
• W2000681096 hasConcept C204232928 @default.
• W2000681096 hasConcept C2780159080 @default.
• W2000681096 hasConcept C2780225610 @default.
• W2000681096 hasConcept C2780827179 @default.
• W2000681096 hasConcept C34688535 @default.
• W2000681096 hasConcept C55493867 @default.
• W2000681096 hasConcept C71924100 @default.
• W2000681096 hasConcept C98274493 @default.
• W2000681096 hasConceptScore W2000681096C103796816 @default.
• W2000681096 hasConceptScore W2000681096C118487528 @default.
• W2000681096 hasConceptScore W2000681096C134018914 @default.
• W2000681096 hasConceptScore W2000681096C142724271 @default.
• W2000681096 hasConceptScore W2000681096C16685009 @default.
• W2000681096 hasConceptScore W2000681096C185592680 @default.
• W2000681096 hasConceptScore W2000681096C190283241 @default.
• W2000681096 hasConceptScore W2000681096C204232928 @default.
• W2000681096 hasConceptScore W2000681096C2780159080 @default.
• W2000681096 hasConceptScore W2000681096C2780225610 @default.
• W2000681096 hasConceptScore W2000681096C2780827179 @default.
• W2000681096 hasConceptScore W2000681096C34688535 @default.
• W2000681096 hasConceptScore W2000681096C55493867 @default.
• W2000681096 hasConceptScore W2000681096C71924100 @default.
• W2000681096 hasConceptScore W2000681096C98274493 @default.
• W2000681096 hasLocation W20006810961 @default.
• W2000681096 hasLocation W20006810962 @default.
• W2000681096 hasOpenAccess W2000681096 @default.
• W2000681096 hasPrimaryLocation W20006810961 @default.
• W2000681096 hasRelatedWork W179953316 @default.
• W2000681096 hasRelatedWork W1943320198 @default.
• W2000681096 hasRelatedWork W1969818728 @default.
• W2000681096 hasRelatedWork W1972449836 @default.
• W2000681096 hasRelatedWork W1979011379 @default.
• W2000681096 hasRelatedWork W1982434025 @default.
• W2000681096 hasRelatedWork W1984877807 @default.
• W2000681096 hasRelatedWork W1996536809 @default.
• W2000681096 hasRelatedWork W2010596393 @default.
• W2000681096 hasRelatedWork W2012488868 @default.
• W2000681096 hasRelatedWork W2013127686 @default.
• W2000681096 hasRelatedWork W2018632493 @default.
• W2000681096 hasRelatedWork W2066996027 @default.
• W2000681096 hasRelatedWork W2134791451 @default.
• W2000681096 hasRelatedWork W2153827036 @default.
• W2000681096 hasRelatedWork W2337209647 @default.
• W2000681096 hasRelatedWork W2396305429 @default.
• W2000681096 hasRelatedWork W2409764263 @default.
• W2000681096 hasRelatedWork W2411238092 @default.
• W2000681096 hasRelatedWork W2938622396 @default.
• W2000681096 isParatext "false" @default.
• W2000681096 isRetracted "false" @default.
• W2000681096 magId "2000681096" @default.

• next