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• W2000685893 abstract "A growing body of evidence shows that immune cells are pivotal in the fight against cancer. First, association studies have identified immune-protective immune response genes against cancer. Second, the presence of immune cells in the respective malignant tumor correlated with a better prognosis for the patients. Third, adoptive cell therapy (ACT) showed, in recent reports, an efficient reduction or even cure for malignant tumors. The focus of this review is a novel in vitro ACT technique, using the patient’s cascade-primed immune cells. The cascade-priming procedure stimulates APCs from the peripheral blood. Stimulated APCs digest and present tumor material better and differentiate naive cytotoxic T-lymphocyte effector cells against the patient’s cancer. The principle and the impressive results of the cascade-primed immune cell treatment in patient case series is compared with the ACT concepts of lymphokine-activated killer, macrophage-activated killer, macrophage-activated killer-dendritic cell, cytokine-induced killer and tumor-infiltrating lymphocyte methods." @default.
• W2000685893 created "2016-06-24" @default.
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• W2000685893 date "2014-03-01" @default.
• W2000685893 modified "2023-09-24" @default.
• W2000685893 title "Benefits of a continuous therapy for cancer patients with a novel adoptive cell therapy by cascade priming (CAPRI)" @default.
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• W2000685893 doi "https://doi.org/10.2217/imt.14.6" @default.
• W2000685893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24762072" @default.
• W2000685893 hasPublicationYear "2014" @default.
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