Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000692241> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2000692241 endingPage "108" @default.
- W2000692241 startingPage "99" @default.
- W2000692241 abstract "Chinese hamsters were treated for two weeks with high doses of chlordiazepoxide hydrochloride, diazepam, and medazepam. Chromosome preparations of bone marrow were made 5–8 h after the last drug application. Single chromatid breaks were found in 0.27% of the cells, an incidence not differing from control values. Cyclophosphamide was used as a known chromosome-breaking control substance in order to test the sensitivity and peculiarities of the bone marrow system. Doses of less than 16 mg/kg produced little chromosome damage whereas after doses of 32 mg/kg the incidence of chromosome aberrations was easily quantitated. The time interval between the last drug application and preparing the bone marrow proved to be of importance: after 10 applications of 64 mg/kg cyclophosphamide in a 14-day course of treatment, the percentage of metaphases with damaged chromosomes dropped from 96% at 6 h after the last medication to 16% at 24 h, 2–5% at 3 days, and to virtually zero after 6 days." @default.
- W2000692241 created "2016-06-24" @default.
- W2000692241 creator A5040366214 @default.
- W2000692241 creator A5048537507 @default.
- W2000692241 date "1969-01-01" @default.
- W2000692241 modified "2023-10-07" @default.
- W2000692241 title "Chromosome studies on bone marrow from Chinese hamsters treated with benzodiazepine tranquillizers and cyclophosphamide" @default.
- W2000692241 cites W2018964283 @default.
- W2000692241 cites W2021008348 @default.
- W2000692241 cites W2345499985 @default.
- W2000692241 cites W2798242231 @default.
- W2000692241 cites W4244069365 @default.
- W2000692241 cites W4362204954 @default.
- W2000692241 doi "https://doi.org/10.1016/0027-5107(69)90053-0" @default.
- W2000692241 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5801080" @default.
- W2000692241 hasPublicationYear "1969" @default.
- W2000692241 type Work @default.
- W2000692241 sameAs 2000692241 @default.
- W2000692241 citedByCount "86" @default.
- W2000692241 countsByYear W20006922412012 @default.
- W2000692241 countsByYear W20006922412014 @default.
- W2000692241 countsByYear W20006922412016 @default.
- W2000692241 crossrefType "journal-article" @default.
- W2000692241 hasAuthorship W2000692241A5040366214 @default.
- W2000692241 hasAuthorship W2000692241A5048537507 @default.
- W2000692241 hasConcept C104317684 @default.
- W2000692241 hasConcept C126322002 @default.
- W2000692241 hasConcept C142724271 @default.
- W2000692241 hasConcept C16685009 @default.
- W2000692241 hasConcept C2776694085 @default.
- W2000692241 hasConcept C2776755627 @default.
- W2000692241 hasConcept C2780007613 @default.
- W2000692241 hasConcept C30481170 @default.
- W2000692241 hasConcept C54355233 @default.
- W2000692241 hasConcept C71924100 @default.
- W2000692241 hasConcept C73397532 @default.
- W2000692241 hasConcept C86803240 @default.
- W2000692241 hasConcept C98274493 @default.
- W2000692241 hasConceptScore W2000692241C104317684 @default.
- W2000692241 hasConceptScore W2000692241C126322002 @default.
- W2000692241 hasConceptScore W2000692241C142724271 @default.
- W2000692241 hasConceptScore W2000692241C16685009 @default.
- W2000692241 hasConceptScore W2000692241C2776694085 @default.
- W2000692241 hasConceptScore W2000692241C2776755627 @default.
- W2000692241 hasConceptScore W2000692241C2780007613 @default.
- W2000692241 hasConceptScore W2000692241C30481170 @default.
- W2000692241 hasConceptScore W2000692241C54355233 @default.
- W2000692241 hasConceptScore W2000692241C71924100 @default.
- W2000692241 hasConceptScore W2000692241C73397532 @default.
- W2000692241 hasConceptScore W2000692241C86803240 @default.
- W2000692241 hasConceptScore W2000692241C98274493 @default.
- W2000692241 hasIssue "1" @default.
- W2000692241 hasLocation W20006922411 @default.
- W2000692241 hasLocation W20006922412 @default.
- W2000692241 hasOpenAccess W2000692241 @default.
- W2000692241 hasPrimaryLocation W20006922411 @default.
- W2000692241 hasRelatedWork W1974335531 @default.
- W2000692241 hasRelatedWork W2013383001 @default.
- W2000692241 hasRelatedWork W2105476183 @default.
- W2000692241 hasRelatedWork W2352165281 @default.
- W2000692241 hasRelatedWork W2366239243 @default.
- W2000692241 hasRelatedWork W2430717863 @default.
- W2000692241 hasRelatedWork W3048798484 @default.
- W2000692241 hasRelatedWork W3088443840 @default.
- W2000692241 hasRelatedWork W4236021575 @default.
- W2000692241 hasRelatedWork W4249342726 @default.
- W2000692241 hasVolume "7" @default.
- W2000692241 isParatext "false" @default.
- W2000692241 isRetracted "false" @default.
- W2000692241 magId "2000692241" @default.
- W2000692241 workType "article" @default.