Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000693555> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2000693555 abstract "Purpose To evaluate the effect of the dietary supplement Nutrof-Total, enriched in antioxidants and fish oil, on retinal fatty acid composition and its potential neuroprotective effect.Methods Six-7 weeks old Sprague Dawley rats were not treated or administrated orally daily with 0,2 ml of water or Nutrof-Total for a period of 10 days. Then, they were sacrificed for fatty acid analysis on plasmas and retinas or they were exposed to bright cyclic light for one week. At the end of light exposure, electroretinograms are recorded and animal are sacrificed for histologic analysis and apoptotic cells detection.Results One week of Nutrof-Total treatment induced a significant increase of EPA, DPA and DHA in the plasma to respectively 163%, 133% and 19%. In the retina, there is also a significant increase of EPA and DPA but not of DHA and LNA is significantly decreased. In parallel, there is a reduced level of omega-6 fatty acid in plasma and retina. In untreated animal, bright-cyclic light induced a reduction of the ONL thickness, an increased in apoptotic cells leading to a reduction of retinal function. Animals treated with Nutrof-total for 10 days before and during the bright cyclic light have a preserved retinal structure, a reduced number of apoptotic cells and a preserved retinal function.Conclusion Nutrof-Total can protect the retina from light-induced retinal damage. Nutrof-Total may be beneficial in preventing the toxic effect of light on the retina.Commercial interest" @default.
- W2000693555 created "2016-06-24" @default.
- W2000693555 creator A5026299789 @default.
- W2000693555 creator A5034394192 @default.
- W2000693555 creator A5039424801 @default.
- W2000693555 creator A5049098372 @default.
- W2000693555 creator A5083236175 @default.
- W2000693555 date "2012-08-06" @default.
- W2000693555 modified "2023-09-24" @default.
- W2000693555 title "Supplement enriched in antioxidants protects the retina from light-induced damage" @default.
- W2000693555 doi "https://doi.org/10.1111/j.1755-3768.2012.f104.x" @default.
- W2000693555 hasPublicationYear "2012" @default.
- W2000693555 type Work @default.
- W2000693555 sameAs 2000693555 @default.
- W2000693555 citedByCount "0" @default.
- W2000693555 crossrefType "journal-article" @default.
- W2000693555 hasAuthorship W2000693555A5026299789 @default.
- W2000693555 hasAuthorship W2000693555A5034394192 @default.
- W2000693555 hasAuthorship W2000693555A5039424801 @default.
- W2000693555 hasAuthorship W2000693555A5049098372 @default.
- W2000693555 hasAuthorship W2000693555A5083236175 @default.
- W2000693555 hasConcept C118487528 @default.
- W2000693555 hasConcept C169760540 @default.
- W2000693555 hasConcept C185592680 @default.
- W2000693555 hasConcept C190283241 @default.
- W2000693555 hasConcept C19038510 @default.
- W2000693555 hasConcept C2777093970 @default.
- W2000693555 hasConcept C2777171753 @default.
- W2000693555 hasConcept C2779946292 @default.
- W2000693555 hasConcept C2780827179 @default.
- W2000693555 hasConcept C2909208804 @default.
- W2000693555 hasConcept C505870484 @default.
- W2000693555 hasConcept C543025807 @default.
- W2000693555 hasConcept C55493867 @default.
- W2000693555 hasConcept C71924100 @default.
- W2000693555 hasConcept C86803240 @default.
- W2000693555 hasConceptScore W2000693555C118487528 @default.
- W2000693555 hasConceptScore W2000693555C169760540 @default.
- W2000693555 hasConceptScore W2000693555C185592680 @default.
- W2000693555 hasConceptScore W2000693555C190283241 @default.
- W2000693555 hasConceptScore W2000693555C19038510 @default.
- W2000693555 hasConceptScore W2000693555C2777093970 @default.
- W2000693555 hasConceptScore W2000693555C2777171753 @default.
- W2000693555 hasConceptScore W2000693555C2779946292 @default.
- W2000693555 hasConceptScore W2000693555C2780827179 @default.
- W2000693555 hasConceptScore W2000693555C2909208804 @default.
- W2000693555 hasConceptScore W2000693555C505870484 @default.
- W2000693555 hasConceptScore W2000693555C543025807 @default.
- W2000693555 hasConceptScore W2000693555C55493867 @default.
- W2000693555 hasConceptScore W2000693555C71924100 @default.
- W2000693555 hasConceptScore W2000693555C86803240 @default.
- W2000693555 hasLocation W20006935551 @default.
- W2000693555 hasOpenAccess W2000693555 @default.
- W2000693555 hasPrimaryLocation W20006935551 @default.
- W2000693555 hasRelatedWork W10752629 @default.
- W2000693555 hasRelatedWork W2022459573 @default.
- W2000693555 hasRelatedWork W2062408023 @default.
- W2000693555 hasRelatedWork W2073688021 @default.
- W2000693555 hasRelatedWork W2348185258 @default.
- W2000693555 hasRelatedWork W2351604240 @default.
- W2000693555 hasRelatedWork W2354117955 @default.
- W2000693555 hasRelatedWork W2370979169 @default.
- W2000693555 hasRelatedWork W2379271742 @default.
- W2000693555 hasRelatedWork W2384719850 @default.
- W2000693555 hasRelatedWork W2392608594 @default.
- W2000693555 hasRelatedWork W2460987884 @default.
- W2000693555 hasRelatedWork W247342323 @default.
- W2000693555 hasRelatedWork W2515581828 @default.
- W2000693555 hasRelatedWork W2638109236 @default.
- W2000693555 hasRelatedWork W3004088830 @default.
- W2000693555 hasRelatedWork W3029064232 @default.
- W2000693555 hasRelatedWork W3032056560 @default.
- W2000693555 hasRelatedWork W3085762597 @default.
- W2000693555 hasRelatedWork W2133742167 @default.
- W2000693555 isParatext "false" @default.
- W2000693555 isRetracted "false" @default.
- W2000693555 magId "2000693555" @default.
- W2000693555 workType "article" @default.