Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000696032> ?p ?o ?g. }
- W2000696032 endingPage "542" @default.
- W2000696032 startingPage "530" @default.
- W2000696032 abstract "Radiation-induced malignant gliomas (RIMGs) are known uncommon risks of brain irradiation. We describe 4 cases of RIMG that occurred at our institution and conduct the largest comprehensive review of the literature to characterize RIMGs better. Patients were identified through the PubMed database. Pearson R linear correlation test was used to evaluate the correlation between radiotherapy (RT) dose and age and latency period. Student t test was used to evaluate differences between latency periods for original tumor lesions. A normalized biologic equivalent dose analysis was performed to indicate the minimum and maximum radiation threshold for neoplasia. A Kaplan-Meier analysis was used to illustrate the overall survival curves. The analysis included 172 cases from the PubMed database and 4 cases occurring at our institution. The median RT dose administered was 35.6 Gy, with the most common dosage ranges being 21–30 Gy (31%) and 41–50 Gy (21.5%). Median latency period was 9 years until diagnosis of RIMG, and RIMG occurred within 15 years in 82% of the patients. There was no correlation between the age of the patient at the time RT was administered (R2 = 0.00081) or amount of RT (R2 = 0.00005) and latency period for RIMG. The mean biologic equivalent dose for neoplasia of a RIMG was 63.3 Gy. The median survival of patients with RIMG improved over time (P = 0.004), with median survival of 9 months before 2007 and 11.5 months after 2007. The risk of RIMG appears to be the same for all age groups, histologies, and RT dosages. Although the risk is low, patients should be aware of RIMG as a possible complication of brain irradiation." @default.
- W2000696032 created "2016-06-24" @default.
- W2000696032 creator A5009596244 @default.
- W2000696032 creator A5026450511 @default.
- W2000696032 creator A5042694519 @default.
- W2000696032 creator A5090095693 @default.
- W2000696032 date "2015-04-01" @default.
- W2000696032 modified "2023-09-30" @default.
- W2000696032 title "Radiation-Induced Malignant Gliomas: A Current Review" @default.
- W2000696032 cites W1486585107 @default.
- W2000696032 cites W1529652591 @default.
- W2000696032 cites W1868055647 @default.
- W2000696032 cites W1967019120 @default.
- W2000696032 cites W1970883372 @default.
- W2000696032 cites W1971252178 @default.
- W2000696032 cites W1971486078 @default.
- W2000696032 cites W1971747664 @default.
- W2000696032 cites W1972456074 @default.
- W2000696032 cites W1972905298 @default.
- W2000696032 cites W1973918698 @default.
- W2000696032 cites W1973952497 @default.
- W2000696032 cites W1975129619 @default.
- W2000696032 cites W1975261511 @default.
- W2000696032 cites W1975303234 @default.
- W2000696032 cites W1977066318 @default.
- W2000696032 cites W1977448039 @default.
- W2000696032 cites W1979335909 @default.
- W2000696032 cites W1979524384 @default.
- W2000696032 cites W1980352578 @default.
- W2000696032 cites W1982986377 @default.
- W2000696032 cites W1983239004 @default.
- W2000696032 cites W1985581645 @default.
- W2000696032 cites W1989332758 @default.
- W2000696032 cites W1992170951 @default.
- W2000696032 cites W1997131934 @default.
- W2000696032 cites W2002134647 @default.
- W2000696032 cites W2005783225 @default.
- W2000696032 cites W2006239422 @default.
- W2000696032 cites W2006464427 @default.
- W2000696032 cites W2006734735 @default.
- W2000696032 cites W2012022214 @default.
- W2000696032 cites W2014875305 @default.
- W2000696032 cites W2020812892 @default.
- W2000696032 cites W2021272226 @default.
- W2000696032 cites W2028038613 @default.
- W2000696032 cites W2031022814 @default.
- W2000696032 cites W2032911689 @default.
- W2000696032 cites W2035038528 @default.
- W2000696032 cites W2036690951 @default.
- W2000696032 cites W2040944375 @default.
- W2000696032 cites W2042269934 @default.
- W2000696032 cites W2043703150 @default.
- W2000696032 cites W2049255312 @default.
- W2000696032 cites W2060212980 @default.
- W2000696032 cites W2062316973 @default.
- W2000696032 cites W2062502792 @default.
- W2000696032 cites W2064626434 @default.
- W2000696032 cites W2065520291 @default.
- W2000696032 cites W2069839439 @default.
- W2000696032 cites W2072789421 @default.
- W2000696032 cites W2078257033 @default.
- W2000696032 cites W2081644032 @default.
- W2000696032 cites W2082111099 @default.
- W2000696032 cites W2082859399 @default.
- W2000696032 cites W2082865841 @default.
- W2000696032 cites W2085283026 @default.
- W2000696032 cites W2086548692 @default.
- W2000696032 cites W2087326019 @default.
- W2000696032 cites W2087763546 @default.
- W2000696032 cites W2089764058 @default.
- W2000696032 cites W2091336109 @default.
- W2000696032 cites W2094197345 @default.
- W2000696032 cites W2094250764 @default.
- W2000696032 cites W2096287682 @default.
- W2000696032 cites W2097691703 @default.
- W2000696032 cites W2099513630 @default.
- W2000696032 cites W2103743547 @default.
- W2000696032 cites W2107007319 @default.
- W2000696032 cites W2114340167 @default.
- W2000696032 cites W2121905592 @default.
- W2000696032 cites W2124968502 @default.
- W2000696032 cites W2129321468 @default.
- W2000696032 cites W2133618766 @default.
- W2000696032 cites W2138549373 @default.
- W2000696032 cites W2141223629 @default.
- W2000696032 cites W2143972655 @default.
- W2000696032 cites W2148289668 @default.
- W2000696032 cites W2152960411 @default.
- W2000696032 cites W2162852959 @default.
- W2000696032 cites W2165118633 @default.
- W2000696032 cites W2173774333 @default.
- W2000696032 cites W2325994549 @default.
- W2000696032 cites W2404097154 @default.
- W2000696032 cites W2443875688 @default.
- W2000696032 cites W2464264807 @default.
- W2000696032 cites W2741095867 @default.
- W2000696032 cites W4235427270 @default.
- W2000696032 cites W4241081028 @default.