FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000698301> ?p ?o ?g. }

• W2000698301 endingPage "418" @default.
• W2000698301 startingPage "411" @default.
• W2000698301 abstract "PurposeExtraprostatic extension (EPE) of tumor conveys an adverse prognosis in early-stage prostate cancer. Previous studies reported on the linear and radial distance of EPE (EPEr) as measured from the prostate edge. In this study, the correlation of the EPEr from a large whole mount prostatectomy series was determined with respect to the needle biopsy and prostatectomy specimen findings.Methods and MaterialsIn a 24-month period, 404 patients underwent radical prostatectomy and the specimens were whole mounted. The preoperative records, biopsy findings, and EPEr from these specimens were evaluated.ResultsThe range of the EPEr distance was 0.0–5.7 mm. A three-category model was used that included 283 patients (70%) with no EPE, 59 (15%) with “near EPE” (range, 0.01–0.59 mm), and 62 (15%) with “far EPE” (≥0.6 mm). Univariate analysis revealed that patient age and prostate volume did not correlate with EPEr, in contrast to all other factors evaluated. Multivariate analysis identified the preoperative serum prostate-specific antigen, the percentage of cancer in the biopsy cores, and clinical tumor stage as significant. However, the Gleason score was not associated with the EPEr. Greater discrimination was possible in estimating the probability of extension in the “near” category than in the “far” category.ConclusionEPEr is associated with the preoperative prostate-specific antigen level, percentage of cancer in the biopsy cores, and clinical tumor stage. These data might be useful in planning local therapies for prostate cancer, but additional studies identifying factors associated with EPEr beyond 3–5 mm could have relevance regarding the appropriate radiotherapeutic management strategies. Extraprostatic extension (EPE) of tumor conveys an adverse prognosis in early-stage prostate cancer. Previous studies reported on the linear and radial distance of EPE (EPEr) as measured from the prostate edge. In this study, the correlation of the EPEr from a large whole mount prostatectomy series was determined with respect to the needle biopsy and prostatectomy specimen findings. In a 24-month period, 404 patients underwent radical prostatectomy and the specimens were whole mounted. The preoperative records, biopsy findings, and EPEr from these specimens were evaluated. The range of the EPEr distance was 0.0–5.7 mm. A three-category model was used that included 283 patients (70%) with no EPE, 59 (15%) with “near EPE” (range, 0.01–0.59 mm), and 62 (15%) with “far EPE” (≥0.6 mm). Univariate analysis revealed that patient age and prostate volume did not correlate with EPEr, in contrast to all other factors evaluated. Multivariate analysis identified the preoperative serum prostate-specific antigen, the percentage of cancer in the biopsy cores, and clinical tumor stage as significant. However, the Gleason score was not associated with the EPEr. Greater discrimination was possible in estimating the probability of extension in the “near” category than in the “far” category. EPEr is associated with the preoperative prostate-specific antigen level, percentage of cancer in the biopsy cores, and clinical tumor stage. These data might be useful in planning local therapies for prostate cancer, but additional studies identifying factors associated with EPEr beyond 3–5 mm could have relevance regarding the appropriate radiotherapeutic management strategies." @default.
• W2000698301 created "2016-06-24" @default.
• W2000698301 creator A5030206457 @default.
• W2000698301 creator A5040586351 @default.
• W2000698301 creator A5043214875 @default.
• W2000698301 creator A5045700400 @default.
• W2000698301 creator A5060306466 @default.
• W2000698301 creator A5065219412 @default.
• W2000698301 creator A5072953177 @default.
• W2000698301 creator A5082725102 @default.
• W2000698301 creator A5087508472 @default.
• W2000698301 date "2007-10-01" @default.
• W2000698301 modified "2023-10-18" @default.
• W2000698301 title "Prediction of Radial Distance of Extraprostatic Extension From Pretherapy Factors" @default.
• W2000698301 cites W156268128 @default.
• W2000698301 cites W1983118050 @default.
• W2000698301 cites W1988094389 @default.
• W2000698301 cites W2005199790 @default.
• W2000698301 cites W2006115709 @default.
• W2000698301 cites W2010397777 @default.
• W2000698301 cites W2022237179 @default.
• W2000698301 cites W2048516791 @default.
• W2000698301 cites W2059487933 @default.
• W2000698301 cites W2060998269 @default.
• W2000698301 cites W2063614609 @default.
• W2000698301 cites W2094804958 @default.
• W2000698301 cites W2098502651 @default.
• W2000698301 cites W2103938269 @default.
• W2000698301 cites W2147953383 @default.
• W2000698301 cites W2171996164 @default.
• W2000698301 cites W2209020482 @default.
• W2000698301 cites W2416860602 @default.
• W2000698301 cites W4245285393 @default.
• W2000698301 cites W4252086282 @default.
• W2000698301 cites W4252605154 @default.
• W2000698301 doi "https://doi.org/10.1016/j.ijrobp.2007.03.016" @default.
• W2000698301 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17869661" @default.
• W2000698301 hasPublicationYear "2007" @default.
• W2000698301 type Work @default.
• W2000698301 sameAs 2000698301 @default.
• W2000698301 citedByCount "17" @default.
• W2000698301 countsByYear W20006983012012 @default.
• W2000698301 countsByYear W20006983012013 @default.
• W2000698301 countsByYear W20006983012014 @default.
• W2000698301 countsByYear W20006983012015 @default.
• W2000698301 countsByYear W20006983012016 @default.
• W2000698301 countsByYear W20006983012017 @default.
• W2000698301 crossrefType "journal-article" @default.
• W2000698301 hasAuthorship W2000698301A5030206457 @default.
• W2000698301 hasAuthorship W2000698301A5040586351 @default.
• W2000698301 hasAuthorship W2000698301A5043214875 @default.
• W2000698301 hasAuthorship W2000698301A5045700400 @default.
• W2000698301 hasAuthorship W2000698301A5060306466 @default.
• W2000698301 hasAuthorship W2000698301A5065219412 @default.
• W2000698301 hasAuthorship W2000698301A5072953177 @default.
• W2000698301 hasAuthorship W2000698301A5082725102 @default.
• W2000698301 hasAuthorship W2000698301A5087508472 @default.
• W2000698301 hasBestOaLocation W20006983011 @default.
• W2000698301 hasConcept C121608353 @default.
• W2000698301 hasConcept C126322002 @default.
• W2000698301 hasConcept C126838900 @default.
• W2000698301 hasConcept C126894567 @default.
• W2000698301 hasConcept C144301174 @default.
• W2000698301 hasConcept C146357865 @default.
• W2000698301 hasConcept C151730666 @default.
• W2000698301 hasConcept C2775934546 @default.
• W2000698301 hasConcept C2776235491 @default.
• W2000698301 hasConcept C2779466945 @default.
• W2000698301 hasConcept C2780192828 @default.
• W2000698301 hasConcept C2781406297 @default.
• W2000698301 hasConcept C38180746 @default.
• W2000698301 hasConcept C63363279 @default.
• W2000698301 hasConcept C71924100 @default.
• W2000698301 hasConcept C86803240 @default.
• W2000698301 hasConceptScore W2000698301C121608353 @default.
• W2000698301 hasConceptScore W2000698301C126322002 @default.
• W2000698301 hasConceptScore W2000698301C126838900 @default.
• W2000698301 hasConceptScore W2000698301C126894567 @default.
• W2000698301 hasConceptScore W2000698301C144301174 @default.
• W2000698301 hasConceptScore W2000698301C146357865 @default.
• W2000698301 hasConceptScore W2000698301C151730666 @default.
• W2000698301 hasConceptScore W2000698301C2775934546 @default.
• W2000698301 hasConceptScore W2000698301C2776235491 @default.
• W2000698301 hasConceptScore W2000698301C2779466945 @default.
• W2000698301 hasConceptScore W2000698301C2780192828 @default.
• W2000698301 hasConceptScore W2000698301C2781406297 @default.
• W2000698301 hasConceptScore W2000698301C38180746 @default.
• W2000698301 hasConceptScore W2000698301C63363279 @default.
• W2000698301 hasConceptScore W2000698301C71924100 @default.
• W2000698301 hasConceptScore W2000698301C86803240 @default.
• W2000698301 hasIssue "2" @default.
• W2000698301 hasLocation W20006983011 @default.
• W2000698301 hasLocation W20006983012 @default.
• W2000698301 hasOpenAccess W2000698301 @default.
• W2000698301 hasPrimaryLocation W20006983011 @default.
• W2000698301 hasRelatedWork W1979374145 @default.
• W2000698301 hasRelatedWork W2041562209 @default.
• W2000698301 hasRelatedWork W2067053628 @default.

• next