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- W2000699455 abstract "With the accelerated aging of human society, Alzheimer's disease (AD) is becoming one of the biggest threats to human health. Since multiple pathogenetic factors are implicated in the disease, the current hitting-one-target therapeutic strategy has proved inefficient to AD. As a result, finding multipotent agents that aim at multiple targets is attracting more and more attention. Although multifunctional anti-AD agents can be created by incorporating two or more pharmacophores in one scaffold, naturally occurring multipotent agents also attracted much attention. In this review, we first describe the functions of some typical naturally originated multipotent anti-AD compounds, then summarize their structural features and reveal that phenolics with certain flexibility predominate in these agents, which are of significance to find novel multipotent drugs to combat AD and other neurodegenerative diseases as well." @default.
- W2000699455 created "2016-06-24" @default.
- W2000699455 creator A5008806398 @default.
- W2000699455 creator A5058691896 @default.
- W2000699455 date "2008-02-01" @default.
- W2000699455 modified "2023-10-07" @default.
- W2000699455 title "Multipotent natural agents to combat Alzheimer's disease. Functional spectrum and structural features" @default.
- W2000699455 cites W1966312971 @default.
- W2000699455 cites W1966893854 @default.
- W2000699455 cites W1968087375 @default.
- W2000699455 cites W1971004115 @default.
- W2000699455 cites W1972355779 @default.
- W2000699455 cites W1973346209 @default.
- W2000699455 cites W1977237543 @default.
- W2000699455 cites W1978190835 @default.
- W2000699455 cites W1979911088 @default.
- W2000699455 cites W1980854377 @default.
- W2000699455 cites W1982685213 @default.
- W2000699455 cites W1984285213 @default.
- W2000699455 cites W1988511555 @default.
- W2000699455 cites W1989251920 @default.
- W2000699455 cites W1991150344 @default.
- W2000699455 cites W1992857406 @default.
- W2000699455 cites W1995200713 @default.
- W2000699455 cites W1997999262 @default.
- W2000699455 cites W1998596454 @default.
- W2000699455 cites W2003593084 @default.
- W2000699455 cites W2004554863 @default.
- W2000699455 cites W2005416088 @default.
- W2000699455 cites W2007236469 @default.
- W2000699455 cites W2007808781 @default.
- W2000699455 cites W2008008517 @default.
- W2000699455 cites W2009789674 @default.
- W2000699455 cites W2010426046 @default.
- W2000699455 cites W2015859691 @default.
- W2000699455 cites W2016698723 @default.
- W2000699455 cites W2020069228 @default.
- W2000699455 cites W2025204606 @default.
- W2000699455 cites W2028545299 @default.
- W2000699455 cites W2038820792 @default.
- W2000699455 cites W2040056112 @default.
- W2000699455 cites W2044460323 @default.
- W2000699455 cites W2044627978 @default.
- W2000699455 cites W2045009959 @default.
- W2000699455 cites W2045261923 @default.
- W2000699455 cites W2047304481 @default.
- W2000699455 cites W2050639031 @default.
- W2000699455 cites W2051376076 @default.
- W2000699455 cites W2058398958 @default.
- W2000699455 cites W2058627553 @default.
- W2000699455 cites W2065922170 @default.
- W2000699455 cites W2066673911 @default.
- W2000699455 cites W2070815033 @default.
- W2000699455 cites W2072179375 @default.
- W2000699455 cites W2075482140 @default.
- W2000699455 cites W2075771060 @default.
- W2000699455 cites W2079294210 @default.
- W2000699455 cites W2079657426 @default.
- W2000699455 cites W2080048320 @default.
- W2000699455 cites W2080274663 @default.
- W2000699455 cites W2083769086 @default.
- W2000699455 cites W2086959952 @default.
- W2000699455 cites W2087238675 @default.
- W2000699455 cites W2094080474 @default.
- W2000699455 cites W2094994507 @default.
- W2000699455 cites W2095337270 @default.
- W2000699455 cites W2108627494 @default.
- W2000699455 cites W2117229834 @default.
- W2000699455 cites W2121963977 @default.
- W2000699455 cites W2122896910 @default.
- W2000699455 cites W2131059456 @default.
- W2000699455 cites W2139241586 @default.
- W2000699455 cites W2146547595 @default.
- W2000699455 cites W2147532876 @default.
- W2000699455 cites W2154508412 @default.
- W2000699455 cites W2154587590 @default.
- W2000699455 cites W2158240118 @default.
- W2000699455 cites W2159373139 @default.
- W2000699455 cites W2159866533 @default.
- W2000699455 cites W2161447669 @default.
- W2000699455 cites W2162566359 @default.
- W2000699455 cites W2167277601 @default.
- W2000699455 cites W2170965675 @default.
- W2000699455 cites W2171081263 @default.
- W2000699455 cites W2238003553 @default.
- W2000699455 cites W4234060991 @default.
- W2000699455 doi "https://doi.org/10.1111/j.1745-7254.2008.00752.x" @default.
- W2000699455 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18215342" @default.
- W2000699455 hasPublicationYear "2008" @default.
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