Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000701615> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2000701615 abstract "To reinvestigate the effect of hCG on circulating and urinary dehydroepiandrosterone sulfate (DHEAS), a hCG stimulation test (5000 IU administered i.m. at 8.30 h on 3 consecutive days) was performed in 6 healthy males (aged 24 to 35 years). Blood specimens and 24-h urine samples were collected immediately before the first and directly after the last hCG administration. Contrary to previous findings in normal men, the present study revealed significant DHEAS responses after testicular stimulation with hCG: plasma DHEAS increased from 7.9 +/- 2.3 to 9.6 +/- 2.2 mumol/L (P < 0.05) and urinary DHEAS from 5.7 +/- 3.6 to 9.3 +/- 5.2 mumol/day (P < 0.05). There was also a marked rise (P < 0.05) in the urinary excretion of total 17-ketosteroid sulfates. Clear increases of unconjugated plasma dehydroepiandrosterone as well as of circulating and renally excreted androstenedione and testosterone definitely confirmed an adequate Leydig cell stimulation. Significant post-hCG changes were additionally observed for plasma and urinary 3 alpha-androstanediol glucuronide (149% and 79% increases, respectively) and for urinary cortisol (21% decrease). Significant correlations were found for the post-hCG percent increases of plasma androstenedione versus plasma DHEAS (r = 0.86) and for the percent increases of plasma testosterone versus urinary DHEAS (r = 0.98), indicating that the extent of gonadal androgen elevations in the circulation of normal men is a determinant of DHEAS increases in blood or urine. These findings provide an explanation for the frequently observed sex differences for DHEAS in adults.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2000701615 created "2016-06-24" @default.
- W2000701615 creator A5048586911 @default.
- W2000701615 creator A5072545388 @default.
- W2000701615 creator A5073666371 @default.
- W2000701615 date "1995-02-01" @default.
- W2000701615 modified "2023-09-23" @default.
- W2000701615 title "Re-examination of the effect of hCG on plasma levels and renal excretion of dehydroepiandrosterone sulfate in healthy males" @default.
- W2000701615 cites W1486397940 @default.
- W2000701615 cites W1964882901 @default.
- W2000701615 cites W1980502392 @default.
- W2000701615 cites W1988351759 @default.
- W2000701615 cites W1989866341 @default.
- W2000701615 cites W2022529700 @default.
- W2000701615 cites W2023823181 @default.
- W2000701615 cites W2025187215 @default.
- W2000701615 cites W2025408121 @default.
- W2000701615 cites W2026977179 @default.
- W2000701615 cites W2033549215 @default.
- W2000701615 cites W2038608615 @default.
- W2000701615 cites W2043040454 @default.
- W2000701615 cites W2054328386 @default.
- W2000701615 cites W2058350561 @default.
- W2000701615 cites W2059120710 @default.
- W2000701615 cites W2073817944 @default.
- W2000701615 cites W2076624838 @default.
- W2000701615 cites W2090408064 @default.
- W2000701615 cites W2096677248 @default.
- W2000701615 cites W2113998582 @default.
- W2000701615 cites W2128297285 @default.
- W2000701615 cites W2142690662 @default.
- W2000701615 cites W2147183786 @default.
- W2000701615 cites W2171142088 @default.
- W2000701615 cites W2339769519 @default.
- W2000701615 cites W2413888007 @default.
- W2000701615 cites W2479518716 @default.
- W2000701615 cites W3187049210 @default.
- W2000701615 cites W566136983 @default.
- W2000701615 cites W575343319 @default.
- W2000701615 cites W654678669 @default.
- W2000701615 doi "https://doi.org/10.1016/0039-128x(94)00040-j" @default.
- W2000701615 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7618186" @default.
- W2000701615 hasPublicationYear "1995" @default.
- W2000701615 type Work @default.
- W2000701615 sameAs 2000701615 @default.
- W2000701615 citedByCount "11" @default.
- W2000701615 countsByYear W20007016152018 @default.
- W2000701615 crossrefType "journal-article" @default.
- W2000701615 hasAuthorship W2000701615A5048586911 @default.
- W2000701615 hasAuthorship W2000701615A5072545388 @default.
- W2000701615 hasAuthorship W2000701615A5073666371 @default.
- W2000701615 hasConcept C10146269 @default.
- W2000701615 hasConcept C126322002 @default.
- W2000701615 hasConcept C134018914 @default.
- W2000701615 hasConcept C185592680 @default.
- W2000701615 hasConcept C2776683971 @default.
- W2000701615 hasConcept C2776992908 @default.
- W2000701615 hasConcept C2777736315 @default.
- W2000701615 hasConcept C2777911890 @default.
- W2000701615 hasConcept C2778575703 @default.
- W2000701615 hasConcept C2779279991 @default.
- W2000701615 hasConcept C2780026642 @default.
- W2000701615 hasConcept C2780657110 @default.
- W2000701615 hasConcept C71315377 @default.
- W2000701615 hasConcept C71924100 @default.
- W2000701615 hasConcept C77411442 @default.
- W2000701615 hasConceptScore W2000701615C10146269 @default.
- W2000701615 hasConceptScore W2000701615C126322002 @default.
- W2000701615 hasConceptScore W2000701615C134018914 @default.
- W2000701615 hasConceptScore W2000701615C185592680 @default.
- W2000701615 hasConceptScore W2000701615C2776683971 @default.
- W2000701615 hasConceptScore W2000701615C2776992908 @default.
- W2000701615 hasConceptScore W2000701615C2777736315 @default.
- W2000701615 hasConceptScore W2000701615C2777911890 @default.
- W2000701615 hasConceptScore W2000701615C2778575703 @default.
- W2000701615 hasConceptScore W2000701615C2779279991 @default.
- W2000701615 hasConceptScore W2000701615C2780026642 @default.
- W2000701615 hasConceptScore W2000701615C2780657110 @default.
- W2000701615 hasConceptScore W2000701615C71315377 @default.
- W2000701615 hasConceptScore W2000701615C71924100 @default.
- W2000701615 hasConceptScore W2000701615C77411442 @default.
- W2000701615 hasLocation W20007016151 @default.
- W2000701615 hasLocation W20007016152 @default.
- W2000701615 hasOpenAccess W2000701615 @default.
- W2000701615 hasPrimaryLocation W20007016151 @default.
- W2000701615 hasRelatedWork W2019114646 @default.
- W2000701615 hasRelatedWork W2036404189 @default.
- W2000701615 hasRelatedWork W2050960029 @default.
- W2000701615 hasRelatedWork W2059210345 @default.
- W2000701615 hasRelatedWork W2076624838 @default.
- W2000701615 hasRelatedWork W2084810910 @default.
- W2000701615 hasRelatedWork W2094630696 @default.
- W2000701615 hasRelatedWork W2101492604 @default.
- W2000701615 hasRelatedWork W2105604113 @default.
- W2000701615 hasRelatedWork W2144746424 @default.
- W2000701615 isParatext "false" @default.
- W2000701615 isRetracted "false" @default.
- W2000701615 magId "2000701615" @default.
- W2000701615 workType "article" @default.