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- W2000703537 abstract "To the Editor: We read with interest the article entitled 'Prevalence of Helicobacter pylori in long-term hemodialysis patients' by Sugimoto et al.1 In this study, Sugimoto et al. reported that compared to patients with normal renal function, the dialysis patients had lower prevalence of H. pylori, which significantly decreased as the duration of dialysis increased, and they still had significant peptic ulcer disease.1 In a 5-year follow-up study of a community screening for H. pylori, Hansen et al.2 reported that H. pylori eradication resulted in a decreased ulcer incidence. Such effect of decrease of prevalence of H. pylori and, therefore, decrease of incidence of peptic ulcer between dialysis and non-dialysis groups seems discrepant.1, 2 We believe that factors aside from H. pylori play an important role in the occurrence of peptic ulcer in dialysis patients. In our 2-year follow-up study after H. pylori eradication, we found that peptic ulcer recurred more in dialysis patients than in non-dialysis patients, with intention to treat analysis (8/32, 25 vs 2/64, 3.1%, P=0.001, OR: 10.000, 95% CI: 1.979–50.540) or per protocol analysis (8/29, 27.5 vs 2/64, 3.1%, P=0.001, OR: 11.429, 95% CI: 2.245–58.168).3" @default.
- W2000703537 created "2016-06-24" @default.
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- W2000703537 date "2009-05-01" @default.
- W2000703537 modified "2023-09-29" @default.
- W2000703537 title "Factors aside from Helicobacter pylori play an important role in the occurrence of peptic ulcer in dialysis patients" @default.
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- W2000703537 doi "https://doi.org/10.1038/ki.2009.26" @default.
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