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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000703622> ?p ?o ?g. }

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• W2000703622 abstract "Chinese hamsters were twice treated with caffeine via stomach tube. The single doses were either 20, 100, 200 or 400 mg per kg body weight. A dose-dependent increase was observed in the frequencies of SCE induced in vivo in bone-marrow cells. Two intraperitoneal injections of the chemical mutagens, cyclophosphamide or benzo[a]pyrene, led to a pronounced increase of the frequency of SCE. Simultaneous applications of the chemical mutagens and caffeine decreased the rate of SCE. The effect of caffeine per se to induce SCE, and the mechanisms by which caffeine reduces the level of SCE induced by chemical mutagens are discussed." @default.
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• W2000703622 date "1979-02-01" @default.
• W2000703622 modified "2023-09-30" @default.
• W2000703622 title "Effects of caffeine on sister-chromatid exchanges (SCE) in vivo" @default.
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• W2000703622 doi "https://doi.org/10.1016/0027-5107(79)90159-3" @default.
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