FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000703860> ?p ?o ?g. }

• W2000703860 endingPage "237" @default.
• W2000703860 startingPage "227" @default.
• W2000703860 abstract "Aim of this study was to examine synaptic connectivity changes in the retina and the location and rate of apoptosis in transgenic S334ter line-3 and line-5 rats with photoreceptor degeneration. Heterozygous S334ter-line-3 and line-5 at P11-13, P30, P60, P90 and several control non-dystrophic rats (Long Evans and Sprague–Dawley) at P60, were studied anatomically by immunohistochemistry for various cell and synaptic markers, and by PNA and TUNEL label.- S334ter line-3 exhibited the fastest rate of degeneration with an early loss of photoreceptors, with 1–2 layers remaining at P30, and only cones left at P60. Line-5 had 4–5 layers left at P30, and very few rods left at P60-90. In both lines, horizontal cell processes (including dendrites and axon) were diminished at P11-13, showing gaps in the outer plexiform layer (OPL) at P60, and at P90, almost no terminal tips could be seen. Bipolar cells showed a retraction of their dendrites forming clusters along the OPL. Synaptic terminals of A-II amacrine cells in the IPL lost most of their parvalbumin-immunoreactivity. The apoptosis rate was different in both lines. Line-3 rats showed many photoreceptors affected at P11, occupying the innermost part of the outer nuclear layer. Line-5 showed a lower number of apoptotic cells within the same location at P13. In summary, the S334ter line-3 rat has a faster progression of degeneration than line-5. The horizontal and bipolar terminals are already affected at P11-P13 in both models. Apoptosis is related to the mutated rhodopsin transgene; the first photoreceptor cells affected are those close to the OPL." @default.
• W2000703860 created "2016-06-24" @default.
• W2000703860 creator A5015983327 @default.
• W2000703860 creator A5018392859 @default.
• W2000703860 creator A5048831711 @default.
• W2000703860 creator A5061924067 @default.
• W2000703860 creator A5063483625 @default.
• W2000703860 creator A5086417397 @default.
• W2000703860 date "2011-03-01" @default.
• W2000703860 modified "2023-10-16" @default.
• W2000703860 title "Retinal degeneration in two lines of transgenic S334ter rats" @default.
• W2000703860 cites W1503520330 @default.
• W2000703860 cites W1545065700 @default.
• W2000703860 cites W1956973213 @default.
• W2000703860 cites W1969659584 @default.
• W2000703860 cites W1975026390 @default.
• W2000703860 cites W1978354922 @default.
• W2000703860 cites W1986126870 @default.
• W2000703860 cites W1986651040 @default.
• W2000703860 cites W1989776650 @default.
• W2000703860 cites W1990976830 @default.
• W2000703860 cites W1991189959 @default.
• W2000703860 cites W1994174270 @default.
• W2000703860 cites W1995620308 @default.
• W2000703860 cites W1998533469 @default.
• W2000703860 cites W2009165363 @default.
• W2000703860 cites W2010029742 @default.
• W2000703860 cites W2012582259 @default.
• W2000703860 cites W2016501339 @default.
• W2000703860 cites W2019739181 @default.
• W2000703860 cites W2021146031 @default.
• W2000703860 cites W2025988461 @default.
• W2000703860 cites W2029479470 @default.
• W2000703860 cites W2032552515 @default.
• W2000703860 cites W2037732277 @default.
• W2000703860 cites W2043201809 @default.
• W2000703860 cites W2048031694 @default.
• W2000703860 cites W2051624031 @default.
• W2000703860 cites W2054434579 @default.
• W2000703860 cites W2056362723 @default.
• W2000703860 cites W2062620004 @default.
• W2000703860 cites W2065059992 @default.
• W2000703860 cites W2067863814 @default.
• W2000703860 cites W2069903330 @default.
• W2000703860 cites W2075390546 @default.
• W2000703860 cites W2077516044 @default.
• W2000703860 cites W2082060456 @default.
• W2000703860 cites W2089767180 @default.
• W2000703860 cites W2100612658 @default.
• W2000703860 cites W2102165670 @default.
• W2000703860 cites W2104429623 @default.
• W2000703860 cites W2134729533 @default.
• W2000703860 cites W2138387337 @default.
• W2000703860 cites W2146547024 @default.
• W2000703860 cites W2147266098 @default.
• W2000703860 cites W2166711233 @default.
• W2000703860 cites W2167809348 @default.
• W2000703860 doi "https://doi.org/10.1016/j.exer.2010.12.001" @default.
• W2000703860 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3073728" @default.
• W2000703860 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21147100" @default.
• W2000703860 hasPublicationYear "2011" @default.
• W2000703860 type Work @default.
• W2000703860 sameAs 2000703860 @default.
• W2000703860 citedByCount "43" @default.
• W2000703860 countsByYear W20007038602012 @default.
• W2000703860 countsByYear W20007038602013 @default.
• W2000703860 countsByYear W20007038602014 @default.
• W2000703860 countsByYear W20007038602015 @default.
• W2000703860 countsByYear W20007038602016 @default.
• W2000703860 countsByYear W20007038602017 @default.
• W2000703860 countsByYear W20007038602018 @default.
• W2000703860 countsByYear W20007038602019 @default.
• W2000703860 countsByYear W20007038602021 @default.
• W2000703860 countsByYear W20007038602022 @default.
• W2000703860 countsByYear W20007038602023 @default.
• W2000703860 crossrefType "journal-article" @default.
• W2000703860 hasAuthorship W2000703860A5015983327 @default.
• W2000703860 hasAuthorship W2000703860A5018392859 @default.
• W2000703860 hasAuthorship W2000703860A5048831711 @default.
• W2000703860 hasAuthorship W2000703860A5061924067 @default.
• W2000703860 hasAuthorship W2000703860A5063483625 @default.
• W2000703860 hasAuthorship W2000703860A5086417397 @default.
• W2000703860 hasBestOaLocation W20007038602 @default.
• W2000703860 hasConcept C105702510 @default.
• W2000703860 hasConcept C169760540 @default.
• W2000703860 hasConcept C185592680 @default.
• W2000703860 hasConcept C190283241 @default.
• W2000703860 hasConcept C2777093970 @default.
• W2000703860 hasConcept C2777585161 @default.
• W2000703860 hasConcept C2778231335 @default.
• W2000703860 hasConcept C2779530196 @default.
• W2000703860 hasConcept C2780827179 @default.
• W2000703860 hasConcept C2780916184 @default.
• W2000703860 hasConcept C2781040256 @default.
• W2000703860 hasConcept C55493867 @default.
• W2000703860 hasConcept C86803240 @default.
• W2000703860 hasConcept C95444343 @default.
• W2000703860 hasConceptScore W2000703860C105702510 @default.

• next