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- W2000704450 abstract "Bilirubin is degraded in the human gut by microflora into urobilinoids. In our study we investigated whether the bilirubin-reducing strain of Clostridium perfringens can reduce bilirubin ditaurate (BDT), a bile pigment of some lower vertebrates, without hydrolysis of the taurine moiety. C. perfringes was incubated under anaerobic conditions with BDT; reduction products were quantified by spectrophotometry and separated by TLC. Based on Rf values of BDT reduction products and synthetic urobilinogen ditaurate, three novel taurine-conjugated urobilinoids were identified. It is likely that bilirubin-reducing enzyme(s) serve for the effective disposal of electrons produced by fermentolytic processes in these anaerobic bacteria." @default.
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- W2000704450 date "2012-04-27" @default.
- W2000704450 modified "2023-10-14" @default.
- W2000704450 title "Reduction of bilirubin ditaurate by the intestinal bacterium Clostridium perfringens." @default.
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- W2000704450 doi "https://doi.org/10.18388/abp.2012_2153" @default.
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