Matches in SemOpenAlex for { <https://semopenalex.org/work/W200070654> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W200070654 abstract "Basic information concerning the molecular organization of the myelin membrane is an intrinsic requirement for understanding the neurochemical events leading to myelination, as well as the potential mechanism of demyelination that might exist at the molecular level for a variety of neurological diseases. The application of chemical, enzymatic, fluorescent, and immunological membrane probes has contributed significantly to this end, although the diverse structural complexity of the myelin sheath has permitted only a rudimentary understanding of its molecular organization. Nevertheless, compelling evidence is accumulating which suggests that components of myelin are asymmetrically distributed in the membrane. Such membrane asymmetry should not only provide important clues to the mechanisms of membrane assembly in the process of myelination, but should also serve as a paradigm for potential functional asymmetry of the individual components at the molecular level. One particularly useful membrane probe is galactose oxidase which has the capacity for identifying surface galactose residues in both glycoproteins and glycolipids on the external surface of the myelin sheath. The identification of these surface components on the myelin sheath is of primary importance since such components might be more readily susceptible to immunological damage or act as a viral receptor which ultimately might lead to demyelination." @default.
- W200070654 created "2016-06-24" @default.
- W200070654 creator A5080381270 @default.
- W200070654 date "1978-01-01" @default.
- W200070654 modified "2023-09-23" @default.
- W200070654 title "The Molecular Architecture of Myelin: Identification of the External Surface Membrane Components" @default.
- W200070654 cites W1967454596 @default.
- W200070654 cites W1985849304 @default.
- W200070654 cites W1989353855 @default.
- W200070654 cites W1991655565 @default.
- W200070654 cites W1992599272 @default.
- W200070654 cites W2006668053 @default.
- W200070654 cites W2026362024 @default.
- W200070654 cites W2044786537 @default.
- W200070654 cites W2046795352 @default.
- W200070654 cites W2048808587 @default.
- W200070654 cites W2050292589 @default.
- W200070654 cites W2071966545 @default.
- W200070654 cites W2078110046 @default.
- W200070654 cites W2089186760 @default.
- W200070654 cites W2090151238 @default.
- W200070654 cites W2092091950 @default.
- W200070654 cites W2119216843 @default.
- W200070654 cites W2170120290 @default.
- W200070654 cites W2205456098 @default.
- W200070654 cites W4301102577 @default.
- W200070654 doi "https://doi.org/10.1007/978-1-4684-2514-7_14" @default.
- W200070654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/696473" @default.
- W200070654 hasPublicationYear "1978" @default.
- W200070654 type Work @default.
- W200070654 sameAs 200070654 @default.
- W200070654 citedByCount "11" @default.
- W200070654 crossrefType "book-chapter" @default.
- W200070654 hasAuthorship W200070654A5080381270 @default.
- W200070654 hasConcept C12554922 @default.
- W200070654 hasConcept C169760540 @default.
- W200070654 hasConcept C181199279 @default.
- W200070654 hasConcept C185592680 @default.
- W200070654 hasConcept C2777438722 @default.
- W200070654 hasConcept C2778609137 @default.
- W200070654 hasConcept C41625074 @default.
- W200070654 hasConcept C529278444 @default.
- W200070654 hasConcept C55493867 @default.
- W200070654 hasConcept C86803240 @default.
- W200070654 hasConcept C95444343 @default.
- W200070654 hasConceptScore W200070654C12554922 @default.
- W200070654 hasConceptScore W200070654C169760540 @default.
- W200070654 hasConceptScore W200070654C181199279 @default.
- W200070654 hasConceptScore W200070654C185592680 @default.
- W200070654 hasConceptScore W200070654C2777438722 @default.
- W200070654 hasConceptScore W200070654C2778609137 @default.
- W200070654 hasConceptScore W200070654C41625074 @default.
- W200070654 hasConceptScore W200070654C529278444 @default.
- W200070654 hasConceptScore W200070654C55493867 @default.
- W200070654 hasConceptScore W200070654C86803240 @default.
- W200070654 hasConceptScore W200070654C95444343 @default.
- W200070654 hasLocation W2000706541 @default.
- W200070654 hasLocation W2000706542 @default.
- W200070654 hasOpenAccess W200070654 @default.
- W200070654 hasPrimaryLocation W2000706541 @default.
- W200070654 hasRelatedWork W1668488797 @default.
- W200070654 hasRelatedWork W2033527080 @default.
- W200070654 hasRelatedWork W2080144430 @default.
- W200070654 hasRelatedWork W2132670847 @default.
- W200070654 hasRelatedWork W2199721082 @default.
- W200070654 hasRelatedWork W2766024997 @default.
- W200070654 hasRelatedWork W2766605844 @default.
- W200070654 hasRelatedWork W3035282130 @default.
- W200070654 hasRelatedWork W3208271389 @default.
- W200070654 hasRelatedWork W4210806336 @default.
- W200070654 isParatext "false" @default.
- W200070654 isRetracted "false" @default.
- W200070654 magId "200070654" @default.
- W200070654 workType "book-chapter" @default.