FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000712391> ?p ?o ?g. }

• W2000712391 endingPage "82" @default.
• W2000712391 startingPage "76" @default.
• W2000712391 abstract "We evaluated the efficacy of adenoviral-mediated gene therapy of experimental spinal cord tumors and the functional outcome after this treatment. Spinal cord tumors were generated in the thoracic region of the spinal cord in Fischer 344 rats by stereotaxic intramedullary injection of 1 x 10(4) 9L gliosarcoma cells. Seven days after tumor cell injection, a replication-defective adenoviral vector carrying the herpes simplex virus thymidine kinase gene (ADV-tk) or a control adenoviral vector carrying the beta-galactosidase gene (ADV-beta gal) was injected into the tumors. Beginning 12 h later the animals were treated with the antiviral drug ganciclovir (GCV; 50 mg/kg) or saline twice a day for 6 days. The neurological performance of the animals was assessed during and following treatment. Eighteen days after tumor cell injection, all of the control animals had paraplegia and large tumors. In contrast, no tumors were detected in animals treated with ADV-tk and GCV. In long-term studies, two of the 5 animals treated with ADV-tk and GCV remained tumor-free and remained neurologically intact at 6 months whereas all animals in the control groups became paraplegic within 18 days." @default.
• W2000712391 created "2016-06-24" @default.
• W2000712391 creator A5010262139 @default.
• W2000712391 creator A5032240853 @default.
• W2000712391 creator A5046134673 @default.
• W2000712391 creator A5054255550 @default.
• W2000712391 creator A5062377680 @default.
• W2000712391 creator A5078680564 @default.
• W2000712391 date "1995-09-11" @default.
• W2000712391 modified "2023-09-27" @default.
• W2000712391 title "Adenovirus-mediated gene therapy for experimental spinal cord tumors: tumoricidal efficacy and functional outcome." @default.
• W2000712391 cites W140890592 @default.
• W2000712391 cites W1791027840 @default.
• W2000712391 cites W1964863866 @default.
• W2000712391 cites W1973504318 @default.
• W2000712391 cites W1999369189 @default.
• W2000712391 cites W2012315955 @default.
• W2000712391 cites W2014804210 @default.
• W2000712391 cites W2016138321 @default.
• W2000712391 cites W2026922744 @default.
• W2000712391 cites W2047275511 @default.
• W2000712391 cites W2053670125 @default.
• W2000712391 cites W2055825871 @default.
• W2000712391 cites W2065434365 @default.
• W2000712391 cites W2094013932 @default.
• W2000712391 cites W2094695920 @default.
• W2000712391 cites W2134712642 @default.
• W2000712391 cites W2137693314 @default.
• W2000712391 cites W2148769388 @default.
• W2000712391 doi "https://doi.org/10.1016/0006-8993(95)00616-x" @default.
• W2000712391 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8590067" @default.
• W2000712391 hasPublicationYear "1995" @default.
• W2000712391 type Work @default.
• W2000712391 sameAs 2000712391 @default.
• W2000712391 citedByCount "22" @default.
• W2000712391 countsByYear W20007123912013 @default.
• W2000712391 countsByYear W20007123912019 @default.
• W2000712391 countsByYear W20007123912020 @default.
• W2000712391 crossrefType "journal-article" @default.
• W2000712391 hasAuthorship W2000712391A5010262139 @default.
• W2000712391 hasAuthorship W2000712391A5032240853 @default.
• W2000712391 hasAuthorship W2000712391A5046134673 @default.
• W2000712391 hasAuthorship W2000712391A5054255550 @default.
• W2000712391 hasAuthorship W2000712391A5062377680 @default.
• W2000712391 hasAuthorship W2000712391A5078680564 @default.
• W2000712391 hasConcept C104317684 @default.
• W2000712391 hasConcept C111599444 @default.
• W2000712391 hasConcept C118552586 @default.
• W2000712391 hasConcept C142724271 @default.
• W2000712391 hasConcept C203014093 @default.
• W2000712391 hasConcept C2522874641 @default.
• W2000712391 hasConcept C2776147627 @default.
• W2000712391 hasConcept C2777295375 @default.
• W2000712391 hasConcept C2777597760 @default.
• W2000712391 hasConcept C2777965375 @default.
• W2000712391 hasConcept C2778227246 @default.
• W2000712391 hasConcept C2779820661 @default.
• W2000712391 hasConcept C2780775167 @default.
• W2000712391 hasConcept C2781196997 @default.
• W2000712391 hasConcept C32470452 @default.
• W2000712391 hasConcept C40767141 @default.
• W2000712391 hasConcept C502942594 @default.
• W2000712391 hasConcept C55493867 @default.
• W2000712391 hasConcept C71924100 @default.
• W2000712391 hasConcept C86803240 @default.
• W2000712391 hasConceptScore W2000712391C104317684 @default.
• W2000712391 hasConceptScore W2000712391C111599444 @default.
• W2000712391 hasConceptScore W2000712391C118552586 @default.
• W2000712391 hasConceptScore W2000712391C142724271 @default.
• W2000712391 hasConceptScore W2000712391C203014093 @default.
• W2000712391 hasConceptScore W2000712391C2522874641 @default.
• W2000712391 hasConceptScore W2000712391C2776147627 @default.
• W2000712391 hasConceptScore W2000712391C2777295375 @default.
• W2000712391 hasConceptScore W2000712391C2777597760 @default.
• W2000712391 hasConceptScore W2000712391C2777965375 @default.
• W2000712391 hasConceptScore W2000712391C2778227246 @default.
• W2000712391 hasConceptScore W2000712391C2779820661 @default.
• W2000712391 hasConceptScore W2000712391C2780775167 @default.
• W2000712391 hasConceptScore W2000712391C2781196997 @default.
• W2000712391 hasConceptScore W2000712391C32470452 @default.
• W2000712391 hasConceptScore W2000712391C40767141 @default.
• W2000712391 hasConceptScore W2000712391C502942594 @default.
• W2000712391 hasConceptScore W2000712391C55493867 @default.
• W2000712391 hasConceptScore W2000712391C71924100 @default.
• W2000712391 hasConceptScore W2000712391C86803240 @default.
• W2000712391 hasIssue "1-2" @default.
• W2000712391 hasLocation W20007123911 @default.
• W2000712391 hasLocation W20007123912 @default.
• W2000712391 hasOpenAccess W2000712391 @default.
• W2000712391 hasPrimaryLocation W20007123911 @default.
• W2000712391 hasRelatedWork W1987617969 @default.
• W2000712391 hasRelatedWork W1994397468 @default.
• W2000712391 hasRelatedWork W2000712391 @default.
• W2000712391 hasRelatedWork W2034108248 @default.
• W2000712391 hasRelatedWork W2083919673 @default.
• W2000712391 hasRelatedWork W2088058542 @default.
• W2000712391 hasRelatedWork W2142305690 @default.
• W2000712391 hasRelatedWork W2319106492 @default.

• next