FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000714852> ?p ?o ?g. }

• W2000714852 endingPage "395" @default.
• W2000714852 startingPage "384" @default.
• W2000714852 abstract "ABSTRACT The Epstein-Barr virus (EBV) Bam HI A mRNAs were originally identified in cDNA libraries from nasopharyngeal carcinoma, where they are expressed at high levels. The RNAs are differentially spliced to form several open reading frames and also contain the BARF0 open reading frame at the 3′ end. One cDNA, RK-BARF0, included a potential endoplasmic reticulum-targeting signal peptide sequence. The RK-BARF0 protein is shown here to interact with the Notch4 ligand binding domain, using yeast two-hybrid screening, coimmunoprecipitation, and confocal microscopy. This interaction induces translocation of a portion of the full-length unprocessed Notch4 to the nucleus by using the Notch nuclear localization signal. These effects of RK-BARF0 on Notch intracellular location indicate that EBV possibly modulates Notch signaling. Unprocessed Notch4 was also detected in immunoprecipitated complexes from EBV-infected cells by using a rabbit antiserum raised against a BARF0-specific peptide. This finding provides additional evidence for expression of RK-BARF0 and its interaction with Notch during EBV infection. In EBV-infected, EBNA2-negative cells, RK-BARF0 induced the expression of EBV latent membrane protein 1 (LMP1), and this induction was dependent on the RK-BARF0/Notch interaction domain. The activation of LMP1 expression by RK-BARF0 may be responsible for expression of LMP1 in EBV latent infections in the absence of EBNA2." @default.
• W2000714852 created "2016-06-24" @default.
• W2000714852 creator A5017114596 @default.
• W2000714852 creator A5022059483 @default.
• W2000714852 date "2001-01-01" @default.
• W2000714852 modified "2023-10-10" @default.
• W2000714852 title "An Epstein-Barr Virus Protein Interacts with Notch" @default.
• W2000714852 cites W1484203766 @default.
• W2000714852 cites W1510154907 @default.
• W2000714852 cites W1524551107 @default.
• W2000714852 cites W1528320858 @default.
• W2000714852 cites W1540402106 @default.
• W2000714852 cites W1541892819 @default.
• W2000714852 cites W1563899879 @default.
• W2000714852 cites W1569815543 @default.
• W2000714852 cites W1648351485 @default.
• W2000714852 cites W1660631781 @default.
• W2000714852 cites W1679753502 @default.
• W2000714852 cites W1725324602 @default.
• W2000714852 cites W1761765142 @default.
• W2000714852 cites W1788882958 @default.
• W2000714852 cites W1812374189 @default.
• W2000714852 cites W1897178313 @default.
• W2000714852 cites W1912140146 @default.
• W2000714852 cites W1935864311 @default.
• W2000714852 cites W1965467050 @default.
• W2000714852 cites W1970269101 @default.
• W2000714852 cites W1975304761 @default.
• W2000714852 cites W1985082049 @default.
• W2000714852 cites W2000550532 @default.
• W2000714852 cites W2015377623 @default.
• W2000714852 cites W2016548488 @default.
• W2000714852 cites W2019107361 @default.
• W2000714852 cites W2020854296 @default.
• W2000714852 cites W2047439787 @default.
• W2000714852 cites W2047604499 @default.
• W2000714852 cites W2059116195 @default.
• W2000714852 cites W2061738087 @default.
• W2000714852 cites W2062084323 @default.
• W2000714852 cites W2074159015 @default.
• W2000714852 cites W2074584250 @default.
• W2000714852 cites W2075357740 @default.
• W2000714852 cites W2079199354 @default.
• W2000714852 cites W2085220509 @default.
• W2000714852 cites W2091513322 @default.
• W2000714852 cites W2097615937 @default.
• W2000714852 cites W2101542976 @default.
• W2000714852 cites W2108491220 @default.
• W2000714852 cites W2143369415 @default.
• W2000714852 cites W2146660065 @default.
• W2000714852 cites W2147550337 @default.
• W2000714852 cites W2149343698 @default.
• W2000714852 cites W2154079565 @default.
• W2000714852 cites W2154872292 @default.
• W2000714852 cites W2156675999 @default.
• W2000714852 cites W2160362993 @default.
• W2000714852 cites W2330560210 @default.
• W2000714852 cites W45568549 @default.
• W2000714852 doi "https://doi.org/10.1128/jvi.75.1.384-395.2001" @default.
• W2000714852 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/113931" @default.
• W2000714852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11119607" @default.
• W2000714852 hasPublicationYear "2001" @default.
• W2000714852 type Work @default.
• W2000714852 sameAs 2000714852 @default.
• W2000714852 citedByCount "53" @default.
• W2000714852 countsByYear W20007148522012 @default.
• W2000714852 countsByYear W20007148522013 @default.
• W2000714852 countsByYear W20007148522014 @default.
• W2000714852 countsByYear W20007148522015 @default.
• W2000714852 countsByYear W20007148522017 @default.
• W2000714852 countsByYear W20007148522022 @default.
• W2000714852 crossrefType "journal-article" @default.
• W2000714852 hasAuthorship W2000714852A5017114596 @default.
• W2000714852 hasAuthorship W2000714852A5022059483 @default.
• W2000714852 hasBestOaLocation W20007148521 @default.
• W2000714852 hasConcept C104317684 @default.
• W2000714852 hasConcept C10858879 @default.
• W2000714852 hasConcept C153911025 @default.
• W2000714852 hasConcept C158617107 @default.
• W2000714852 hasConcept C159047783 @default.
• W2000714852 hasConcept C161879069 @default.
• W2000714852 hasConcept C167625842 @default.
• W2000714852 hasConcept C187882448 @default.
• W2000714852 hasConcept C2522874641 @default.
• W2000714852 hasConcept C47289529 @default.
• W2000714852 hasConcept C54355233 @default.
• W2000714852 hasConcept C62478195 @default.
• W2000714852 hasConcept C71829478 @default.
• W2000714852 hasConcept C86803240 @default.
• W2000714852 hasConcept C95444343 @default.
• W2000714852 hasConceptScore W2000714852C104317684 @default.
• W2000714852 hasConceptScore W2000714852C10858879 @default.
• W2000714852 hasConceptScore W2000714852C153911025 @default.
• W2000714852 hasConceptScore W2000714852C158617107 @default.
• W2000714852 hasConceptScore W2000714852C159047783 @default.
• W2000714852 hasConceptScore W2000714852C161879069 @default.
• W2000714852 hasConceptScore W2000714852C167625842 @default.
• W2000714852 hasConceptScore W2000714852C187882448 @default.

• next