FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000717257> ?p ?o ?g. }

• W2000717257 endingPage "1713" @default.
• W2000717257 startingPage "1705" @default.
• W2000717257 abstract "In general, a rapidly growing epithelial sheet during tissue morphogenesis shows a smooth and continuous curvature on both inner cavity (apical) and basement membrane (basal) sides. For instance, epithelia of the neural tube and optic vesicle in the early embryo maintain continuous curvatures in their local domains, even during their rapid growth. However, given that cell divisions, which substantially perturb the local force balance, frequently and successively occur in an uncoordinated manner, it is not self-evident to explain how the tissue keeps a continuous curvature at large. In the majority of developing embryonic epithelia with smooth surfaces, their curvatures are apically concave, because of the presence of strong tangential contractile force on the apical side. In this numerical study, we demonstrate that tangential contractile forces on the apical surface play a critical role in the maintenance of smooth curvatures in the epithelium and reduce irregular undulations caused by uncoordinated generation of local pushing force. Using a reversible network reconnection (RNR) model, which we previously developed to make numerical analyses highly reproducible even under rapid tissue-growth conditions, we performed simulations for morphodynamics to examine the effect of apical contractile forces on the continuity of curvatures. Interestingly, the presence of apical contractile forces suppressed irregular undulations not only on the apical side but also on the basal surface. These results indicate that cellular contractile forces on the apical surface control not only the shape at a single cell level but also at a tissue level as a result of emergent mechanical coordination." @default.
• W2000717257 created "2016-06-24" @default.
• W2000717257 creator A5024222736 @default.
• W2000717257 creator A5059692464 @default.
• W2000717257 creator A5067131951 @default.
• W2000717257 creator A5068146087 @default.
• W2000717257 creator A5077161039 @default.
• W2000717257 date "2013-06-01" @default.
• W2000717257 modified "2023-09-25" @default.
• W2000717257 title "Apical contractility in growing epithelium supports robust maintenance of smooth curvatures against cell-division-induced mechanical disturbance" @default.
• W2000717257 cites W1540618004 @default.
• W2000717257 cites W1554042779 @default.
• W2000717257 cites W1575303802 @default.
• W2000717257 cites W1979366429 @default.
• W2000717257 cites W1989184968 @default.
• W2000717257 cites W1992260947 @default.
• W2000717257 cites W2000618372 @default.
• W2000717257 cites W2024425536 @default.
• W2000717257 cites W2047656863 @default.
• W2000717257 cites W2074314696 @default.
• W2000717257 cites W2099954462 @default.
• W2000717257 cites W2115856515 @default.
• W2000717257 cites W2119930934 @default.
• W2000717257 cites W2130735747 @default.
• W2000717257 cites W2140753536 @default.
• W2000717257 cites W2154994078 @default.
• W2000717257 cites W2155154349 @default.
• W2000717257 cites W2170794368 @default.
• W2000717257 doi "https://doi.org/10.1016/j.jbiomech.2013.03.035" @default.
• W2000717257 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23676291" @default.
• W2000717257 hasPublicationYear "2013" @default.
• W2000717257 type Work @default.
• W2000717257 sameAs 2000717257 @default.
• W2000717257 citedByCount "31" @default.
• W2000717257 countsByYear W20007172572014 @default.
• W2000717257 countsByYear W20007172572015 @default.
• W2000717257 countsByYear W20007172572016 @default.
• W2000717257 countsByYear W20007172572017 @default.
• W2000717257 countsByYear W20007172572018 @default.
• W2000717257 countsByYear W20007172572019 @default.
• W2000717257 countsByYear W20007172572020 @default.
• W2000717257 countsByYear W20007172572022 @default.
• W2000717257 countsByYear W20007172572023 @default.
• W2000717257 crossrefType "journal-article" @default.
• W2000717257 hasAuthorship W2000717257A5024222736 @default.
• W2000717257 hasAuthorship W2000717257A5059692464 @default.
• W2000717257 hasAuthorship W2000717257A5067131951 @default.
• W2000717257 hasAuthorship W2000717257A5068146087 @default.
• W2000717257 hasAuthorship W2000717257A5077161039 @default.
• W2000717257 hasBestOaLocation W20007172572 @default.
• W2000717257 hasConcept C104317684 @default.
• W2000717257 hasConcept C105702510 @default.
• W2000717257 hasConcept C121332964 @default.
• W2000717257 hasConcept C12554922 @default.
• W2000717257 hasConcept C134018914 @default.
• W2000717257 hasConcept C176080148 @default.
• W2000717257 hasConcept C185592680 @default.
• W2000717257 hasConcept C195065555 @default.
• W2000717257 hasConcept C2524010 @default.
• W2000717257 hasConcept C3018436504 @default.
• W2000717257 hasConcept C33923547 @default.
• W2000717257 hasConcept C39133596 @default.
• W2000717257 hasConcept C39579648 @default.
• W2000717257 hasConcept C40692019 @default.
• W2000717257 hasConcept C529295009 @default.
• W2000717257 hasConcept C54355233 @default.
• W2000717257 hasConcept C55493867 @default.
• W2000717257 hasConcept C57879066 @default.
• W2000717257 hasConcept C86803240 @default.
• W2000717257 hasConcept C95444343 @default.
• W2000717257 hasConceptScore W2000717257C104317684 @default.
• W2000717257 hasConceptScore W2000717257C105702510 @default.
• W2000717257 hasConceptScore W2000717257C121332964 @default.
• W2000717257 hasConceptScore W2000717257C12554922 @default.
• W2000717257 hasConceptScore W2000717257C134018914 @default.
• W2000717257 hasConceptScore W2000717257C176080148 @default.
• W2000717257 hasConceptScore W2000717257C185592680 @default.
• W2000717257 hasConceptScore W2000717257C195065555 @default.
• W2000717257 hasConceptScore W2000717257C2524010 @default.
• W2000717257 hasConceptScore W2000717257C3018436504 @default.
• W2000717257 hasConceptScore W2000717257C33923547 @default.
• W2000717257 hasConceptScore W2000717257C39133596 @default.
• W2000717257 hasConceptScore W2000717257C39579648 @default.
• W2000717257 hasConceptScore W2000717257C40692019 @default.
• W2000717257 hasConceptScore W2000717257C529295009 @default.
• W2000717257 hasConceptScore W2000717257C54355233 @default.
• W2000717257 hasConceptScore W2000717257C55493867 @default.
• W2000717257 hasConceptScore W2000717257C57879066 @default.
• W2000717257 hasConceptScore W2000717257C86803240 @default.
• W2000717257 hasConceptScore W2000717257C95444343 @default.
• W2000717257 hasIssue "10" @default.
• W2000717257 hasLocation W20007172571 @default.
• W2000717257 hasLocation W20007172572 @default.
• W2000717257 hasLocation W20007172573 @default.
• W2000717257 hasOpenAccess W2000717257 @default.
• W2000717257 hasPrimaryLocation W20007172571 @default.
• W2000717257 hasRelatedWork W2002941882 @default.
• W2000717257 hasRelatedWork W2120053065 @default.

• next